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Rabbit Anti-Myoglobin/HRP Conjugated antibody (bs-41107R-HRP)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-41107R-HRP
英文名稱 Rabbit Anti-Myoglobin/HRP Conjugated antibody
中文名稱 辣根過氧化物酶標(biāo)記的肌紅蛋白抗體
別    名 MYO; MB; MGC13548; PVALB; MYG_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  心血管  細(xì)胞生物  免疫學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, 
產(chǎn)品應(yīng)用 WB=1:500-2000 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 17kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 Purified Human Myoglobin (Natural Human Myoglobin protein)
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 Constituents: 0.01M PBS, pH 7.4 with 10 mg/mL BSA and 0.1% Gentamicin, 50% glycerol. Or Lyophilized. Buffer = 0.01M PBS, pH 7.4 with 10 mg/mL BSA and 0.1% Gentamicin. Reconstitute with sterile distilled water.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Myoglobin is a small heme containing protein responsible for the oxygen deposition in muscle tissues. Only one form of myoglobin is expressed in cardiac and skeletal muscles. Myoglobin is known as a marker of myocardial damage and it has been used for more than three decades. Nowadays it still is very commonly used in clinical practice as an early marker of AMI. It appears in patient's blood 1 to 3 hours after onset of the symptoms, reaching peak level within 8 to 12 hours. Myoglobin is not so cardiac specific as cTnI or cTnT. Because of high myoglobin concentration in skeletal muscle tissue, even minor skeletal muscle injury results in the significant increase of myoglobin concentration in blood. Thus myoglobin is used together with cTnI or cTnT in clinical practise for better specificity in AMI diagnosis.

Function:
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.

Similarity:
Belongs to the globin family.

Database links:

Entrez Gene: 4151 Human

Entrez Gene: 17189 Mouse

Entrez Gene: 59108 Rat

Omim: 160000 Human

SwissProt: P02144 Human

SwissProt: P04247 Mouse

SwissProt: Q9QZ76 Rat

Unigene: 517586 Human

Unigene: 404074 Mouse

Unigene: 40511 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

肌紅蛋白存在于肌肉中,心肌中含量特別豐富,,有較高的組織特異性,是橫紋肌的特異性標(biāo)記物,但對腫瘤的敏感性較差。主要用于橫紋肌腫瘤的診斷與鑒別診斷。少數(shù)惡性中胚葉混合瘤、睪丸畸胎瘤、腎母細(xì)胞瘤亦可見陽性表達(dá)。
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