| 產(chǎn)品編號(hào) | bs-21147R-BF647 |
| 英文名稱(chēng)1 | Rabbit Anti-RALGPS1/BF647 Conjugated antibody |
| 中文名稱(chēng) | BF647標(biāo)記的RALGPS1蛋白抗體 |
| 別 名 | Ral GEF with PH domain and SH3 binding motif 1; RalA exchange factor RalGPS1; RALGEF2; RALGPS1A; Ras specific guanine nucleotide releasing factor RalGPS1. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買(mǎi) 大包裝/詢(xún)價(jià) |
| 說(shuō) 明 書(shū) | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) G蛋白信號(hào) |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | Mouse, (predicted: Human, Rat, Chicken, Dog, Cow, Horse, Rabbit, Sheep, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 62kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human RALGPS1 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: May be involved in cytoskeletal organization (By similarity). May also be involved in the stimulation of transcription in a Ras independent fashion (By similarity). Guanine nucleotide exchange factor for the small GTPase RALA. Six different isoforms have been described. Function: Guanine nucleotide exchange factor (GEF) for the small GTPase RALA. May be involved in cytoskeletal organization (By similarity). Guanine nucleotide exchange factor for. Subunit: Interacts with the SH3 domains of GRB2, NCK1, PLCG1 and SRC. Subcellular Location: Cell Membrane and Cytoplasmic. Tissue Specificity: Widely expressed (at protein level). Isoform 2 is expressed in brain, colon, kidney, pancreas, prostate, skeletal muscle, small intestine, testis, thymus and uterus. Isoform 1 is expressed at high levels in heart and testis and at lower levels in brain, pancreas, skeletal muscle, small intestine and thymus. Database links: Entrez Gene: 9649 Human SwissProt: Q5JS13 Human Unigene: 648175 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
