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Rabbit Anti-SEZ6L2/Gold Conjugated antibody (bs-21102R-Gold)
訂購熱線:400-901-9800
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-21102R-Gold
英文名稱 Rabbit Anti-SEZ6L2/Gold Conjugated antibody
中文名稱 膠體金標記的癲癇相關蛋白6樣蛋白2抗體
別    名 FLJ90517; PSK 1; PSK; SE6L2_HUMAN; Seizure 6 like protein 2; Seizure 6-like protein 2; Seizure related 6 homolog (mouse) like 2; SEZ6L2; Type I transmembrane receptor (seizure related protein).  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 神經生物學  信號轉導  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 98kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SEZ6L2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
This gene encodes a seizure-related protein that is localized on the cell surface. The gene is located in a region of chromosome 16p11.2 that is thought to contain candidate genes for autism spectrum disorders (ASD), though there is no evidence directly implicating this gene in ASD. Increased expression of this gene has been found in lung cancers, and the protein is therefore considered to be a novel prognostic marker for lung cancer. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]

Function:
Protein-lysine N-methyltransferase that specifically monomethylates 'Lys-310' of the RELA subunit of NF-kappa-B complex, leading to down-regulate NF-kappa-B transcription factor activity.

Subcellular Location:
Cell membrane. Endoplasmic reticulum membrane. Detected on cell surface of lung-cancer.

Post-translational modifications:
O-glycosylated with core 1 or possibly core 8 glycans.

Similarity:
Belongs to the SEZ6 family.
Contains 3 CUB domains.
Contains 5 Sushi (CCP/SCR) domains.

Database links:

Entrez Gene: 26470 Human

SwissProt: Q29RN8 Cow

SwissProt: Q6UXD5 Human

SwissProt: Q6AX42 Xenopus laevis

Unigene: 6314 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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