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Rabbit Anti-RBMS1/Cervical cancer oncogene 4/AP Conjugated antibody (bs-19776R-AP)
訂購熱線:400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-19776R-AP
英文名稱 Rabbit Anti-RBMS1/Cervical cancer oncogene 4/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標記的宮頸癌癌基因4抗體
別    名 c myc gene single strand binding protein 2; C2orf12; Cervical cancer oncogene 4; HCC 4; MSSP 2; MSSP 3; MSSP; MSSP-1; MSSP-2; MSSP-3; MSSP1; RBMS1; RBMS1_HUMAN; RNA binding motif, single stranded interacting protein 1; RNA-binding motif; SCR2; Single stranded DNA binding protein MSSP 1; Single-stranded DNA-binding protein MSSP-1; single-stranded-interacting protein 1; suppressor of cdc 2 (cdc13) with RNA binding motif 2; Suppressor of CDC2 with RNA binding motif 2; Suppressor of CDC2 with RNA-binding motif 2; YC1.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞凋亡  細胞周期蛋白  轉錄調節因子  結合蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產品應用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 45kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RBMS1/Cervical cancer oncogene 4
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. Several transcript variants, resulting from alternative splicing and encoding different isoforms, have been described. A pseudogene for this locus is found on chromosome 12. [provided by RefSeq, Feb 2009]

Function:
Single-stranded DNA binding protein that interacts with the region upstream of the MYC gene. Binds specifically to the DNA sequence motif 5'-[AT]CT[AT][AT]T-3'. Probably has a role in DNA replication.

Subcellular Location:
Nucleus.

Tissue Specificity:
Highest amounts are found in placenta, lung and heart.

Similarity:
Contains 2 RRM (RNA recognition motif) domains.

Database links:

Entrez Gene: 395880 Chicken

Entrez Gene: 526135 Cow

Entrez Gene: 5937 Human

Entrez Gene: 56878 Mouse

Entrez Gene: 362138 Rat

GenBank: NP_058520.1 Human

Omim: 602310 Human

SwissProt: Q3ZBP3 Cow

SwissProt: P29558 Human

SwissProt: Q91W59 Mouse

SwissProt: Q5PQP1 Rat

Unigene: 470412 Human

Unigene: 708357 Human

Unigene: 259667 Mouse

Unigene: 482338 Mouse

Unigene: 98522 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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