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Rabbit Anti-USP52/Pan2/Gold Conjugated antibody (bs-21012R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-21012R-Gold
英文名稱1 Rabbit Anti-USP52/Pan2/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的泛素特異性蛋白酶52抗體
別    名 hPan2; Inactive ubiquitin carboxyl terminal hydrolase 52; Inactive ubiquitin carboxyl-terminal hydrolase 52; KIAA0710; PAB dependent poly(A) specific ribonuclease subunit 2; PAB-dependent poly(A)-specific ribonuclease subunit 2; PABP dependent poly(A) nuclease 2; PAN 2; PAN2; PAN2 homolog PABP1 dependent poly A specific ribonuclease subunit; PAN2 poly(A) specific ribonuclease subunit homolog; PAN2 polyA specific ribonuclease subunit homolog; PAN2_HUMAN; Ubiquitin specific peptidase 52; Ubiquitin specific protease 52; USP 52; USP52.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 細(xì)胞生物  發(fā)育生物學(xué)  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  泛素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Rabbit, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 135kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human USP52/Pan2
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
This gene encodes a deadenylase that functions as the catalytic subunit of the polyadenylate binding protein dependent poly(A) nuclease complex. The encoded protein is a magnesium dependent 3' to 5' exoribonuclease that is involved in the degradation of cytoplasmic mRNAs. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

Function:
Functions in cytoplasmic mRNA decay. As part of the Pan nuclease complex, shortens poly(A) tails of RNA when the poly(A) stretch is bound by polyadenylate-binding protein.

Subcellular Location:
Cytoplasm. Nucleus. Shuttles between nucleus and cytoplasm.

Similarity:
Belongs to the peptidase C19 family.
PAN2 subfamily.
Contains 1 exonuclease domain.

Database links:

Entrez Gene: 9924 Human

Entrez Gene: 103135 Mouse

Entrez Gene: 408200 Rat

SwissProt: Q504Q3 Human

SwissProt: Q8BGF7 Mouse

SwissProt: Q6IE70 Rat

Unigene: 273397 Human

Unigene: 244183 Mouse

Unigene: 9091 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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