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Rabbit Anti-phospho-RGS16 (Tyr168)/BF594 Conjugated antibody (bs-19856R-BF594)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-19856R-BF594
英文名稱1 Rabbit Anti-phospho-RGS16 (Tyr168)/BF594 Conjugated antibody
中文名稱 BF594標記的磷酸化G蛋白信號轉導調節因子16抗體
別    名 RGS16 (phospho Y168); p-RGS16 (phospho Y168); A28 RGS14; A28 RGS14P; A28-RGS14P; HGNC:9997; hRGS-r; OTTHUMP00000033147; Regulator of G protein signaling 16; Regulator of G protein signalling 16; Regulator of G-protein signaling 16; Retinal-specific RGS; Retinally abundant regulator of G protein signaling; Retinally abundant regulator of G-protein signaling; RGS 16; RGS R; RGS-R; Rgs14; RGS16; RGS16_HUMAN; RGSR.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
產品類型 磷酸化抗體 
研究領域 細胞生物  信號轉導  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 23kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human RGS16 around the phosphorylation site of Tyr168
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The protein encoded by this gene belongs to the 'regulator of G protein signaling' family. It inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits. It also may play a role in regulating the kinetics of signaling in the phototransduction cascade. [provided by RefSeq, Jul 2008]

Function:
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha. May play a role in regulating the kinetics of signaling in the phototransduction cascade.

Tissue Specificity:
Abundantly expressed in retina with lower levels of expression in most other tissues.

Post-translational modifications:
Palmitoylated on Cys-2 and/or Cys-12.
Phosphorylation on Tyr-168 upon EGFR stimulation. Enhanced GTPase accelerating (GAP) activity on G(i)-alpha.

Similarity:
Contains 1 RGS domain.

Database links:

Entrez Gene: 6004 Human

Entrez Gene: 19734 Mouse

Omim: 602514 Human

SwissProt: O15492 Human

SwissProt: P97428 Mouse

Unigene: 413297 Human

Unigene: 181709 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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