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Rabbit Anti-SNRPN/Cy7 Conjugated antibody (bs-8741R-Cy7)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號 bs-8741R-Cy7
英文名稱1 Rabbit Anti-SNRPN/Cy7 Conjugated antibody
中文名稱 Cy7標(biāo)記的小核糖核蛋白N抗體
別    名 HCERN3; PWCR; RSMN_HUMAN; RT LI; RTLI; SM D; Sm N; Sm protein D; Sm protein N; Sm-D; Sm-N; Small nuclear ribonucleoprotein associated protein N; Small nuclear ribonucleoprotein polypeptide N; Small nuclear ribonucleoprotein-associated protein N; SMD; SmN; SNRNP N; snRNP-N; SNRNPN; SNRPN; SNURF SNRPN; Tissue specific splicing protein; Tissue-specific-splicing protein.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 25kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SNRPN
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene is located within the Prader-Willi Syndrome critical region on chromosome 15 and is imprinted and expressed from the paternal allele. It encodes a component of the small nuclear ribonucleoprotein complex, which functions in pre-mRNA processing and may contribute to tissue-specific alternative splicing. Alternative promoter use and alternative splicing result in a multitude of transcript variants encoding the same protein. Transcript variants that initiate at the CpG island-associated imprinting center may be bicistronic and also encode the SNRPN upstream reading frame protein (SNURF) from an upstream open reading frame. In addition, long spliced transcripts for small nucleolar RNA host gene 14 (SNHG14) may originate from the promoters at this locus and share exons with this gene. Alterations in this region are associated with parental imprint switch failure, which may cause Angelman syndrome or Prader-Willi syndrome. [provided by RefSeq, Mar 2017]

Function:
May be involved in tissue-specific alternative RNA processing events.

Subcellular Location:
Nucleus.

Tissue Specificity:
Expressed in brain and lymphoblasts.

Similarity:
Belongs to the snRNP SmB/SmN family.

Database links:

Entrez Gene: 780877 Cow

Entrez Gene: 6638 Human

Entrez Gene: 20646 Mouse

Entrez Gene: 84704 Mouse

Entrez Gene: 81781 Rat

Omim: 182279 Human

SwissProt: Q17QN3 Cow

SwissProt: Q60HD3 Cynomolgus Monkey

SwissProt: P63162 Human

SwissProt: P63163 Mouse

SwissProt: Q5R6I0 Orangutan

SwissProt: P63164 Rat

Unigene: 555970 Human

Unigene: 564847 Human

Unigene: 578619 Human

Unigene: 585703 Human

Unigene: 592473 Human

Unigene: 621316 Human

Unigene: 632166 Human

Unigene: 728856 Human

Unigene: 274995 Mouse

Unigene: 11169 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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