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Rabbit Anti-MRPS18A/Gold Conjugated antibody (bs-17815R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-17815R-Gold
英文名稱1 Rabbit Anti-MRPS18A/Gold Conjugated antibody
中文名稱 膠體金標記的線粒體核糖體蛋白S18A抗體
別    名 28S ribosomal protein S18 3 mitochondrial; 28S ribosomal protein S18a mitochondrial; HumanS18b; mitochondrial ribosomal protein S18 3; mitochondrial ribosomal protein S18A; MRP S18 3; MRP S18 a; MRPS18 3; S18bmt; S18mt a.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 細胞生物  轉錄調節因子  細胞類型標志物  線粒體  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Sheep, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 19kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MRPS18A
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins. A pseudogene corresponding to this gene is found on chromosome 3p. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jul 2010]

Function:
MRPS18A is 1 of more than 70 protein components of mitochondrial ribosomes which are encoded by the nuclear genome. Mitochondria have their own translation system for production of 13 proteins essential for oxidative phosphorylation.

Subcellular Location:
Mitochondrial

Similarity:
Belongs to the ribosomal protein S18P family.

Database links:

Entrez Gene: 55168 Human

Omim: 611981 Human

SwissProt: Q9NVS2 Human

Unigene: 520149 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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