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Rabbit Anti-HRC/APC Conjugated antibody (bs-17387R-APC)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-17387R-APC
英文名稱 Rabbit Anti-HRC/APC Conjugated antibody
中文名稱 APC標(biāo)記的HRC蛋白抗體
別    名 HCP; HRC; HRC histidine rich calcium binding protein; MGC133236; Sarcoplasmic reticulum histidine-rich calcium-binding protein; SRCH_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  結(jié)合蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, 
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 77kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HRC
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
HRC is a 699 amino acid that binds low-density lipoprotein with high affinity. As a high capacity calcium binding protein, HRC regulates the sequestration and release of calcium in the lumen of the junctional sarcoplasmic reticulum (SR) of cardiac, skeletal and smooth muscle. This mechanism may involve direct interaction between HRC and the cytoplasmic domain of Triadin, an integral membrane protein of the SR. The gene encoding HRC maps to human chromosome 19q13.33 and mouse chromosome 7 B4

Function:
May play a role in the regulation of calcium sequestration or release in the SR of skeletal and cardiac muscle.

Subcellular Location:
Sarcoplasmic reticulum lumen.

Similarity:
To rabbit HRC.

Database links:

Entrez Gene: 3270 Human

Omim: 142705 Human

SwissProt: P23327 Human

Unigene: 436885 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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