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Rabbit Anti-hnRNP A0/Cy5 Conjugated antibody (bs-17339R-Cy5)
訂購熱線:400-901-9800
訂購郵箱:sales@www.chomd.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@www.chomd.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-17339R-Cy5
英文名稱 Rabbit Anti-hnRNP A0/Cy5 Conjugated antibody
中文名稱 Cy5標記的異質核糖核蛋白A0抗體
別    名 HNRNPA0; Heterogeneous nuclear ribonucleoprotein A0; hnRNA binding protein; hnRNP A0; HNRNPA0; ROA0_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  結合蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, Rabbit, Sheep, Cynomolgus Monkey, Rhesus monkey, Gorilla, Marmoset (common))
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 31kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human hnRNP A0
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Heterogeneous nuclear ribonucleoproteins (hnRNPs) constitute a set of polypeptides that contribute to mRNA transcription and pre-mRNA processing as well as mature mRNA transport to the cytoplasm and translation. They also bind heterogeneous nuclear RNA (hnRNA), which are the transcripts produced by RNA polymerase II. There are approximately 20 known hnRNP proteins and their complexes are the major constituents of the spliceosome. The majority of hnRNP protein components are localized to the nucleus; however, some shuttle between the nucleus and the cytoplasm. hnRNP I, also designated polypyrimidine tract-binding protein (PTB), and its homolog hnRNP L, bind to the 3' end of introns to modulate alternative splicing mechanisms of pre-mRNAs in normal cells and the translation of sev-eral viruses, including hepatitis C virus (HCV). The human hnRNP I gene maps to chromosome 19p13.3 and encodes a protein that is localized in the nucleoplasm. hnRNP L, like hnRNP I, is also localized in the nucleoplasm.

Function:
This protein is a component of ribonucleosomes.

Subcellular Location:
Nucleus. Component of ribonucleosomes.

Post-translational modifications:
Arg-291 is dimethylated, probably to asymmetric dimethylarginine.

Similarity:
Contains 2 RRM (RNA recognition motif) domains.

Database links:

Entrez Gene: 416302 Chicken

Entrez Gene: 745876 Chimpanzee

Entrez Gene: 540311 Cow

Entrez Gene: 481524 Dog

Entrez Gene: 10949 Human

Entrez Gene: 77134 Mouse

Entrez Gene: 498696 Rat

Omim: 609409 Human

SwissProt: Q13151 Human

SwissProt: Q9CX86 Mouse

Unigene: 645902 Human

Unigene: 96996 Human

Unigene: 490274 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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