| 產品編號 | bs-16525R-PE-Cy5 |
| 英文名稱1 | Rabbit Anti-ZNF675/PE-Cy5 Conjugated antibody |
| 中文名稱 | PE-Cy5標記的鋅指蛋白675抗體 |
| 別 名 | FLJ36350; TBZF; TIZ; TRAF6-binding zinc finger protein; TRAF6-inhibitory zinc finger protein; Zinc finger protein 675; ZN675_HUMAN; ZNF 675; ZNF675. |
| 規格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領域 | 轉錄調節因子 鋅指蛋白 表觀遺傳學 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應 | (predicted: Human, ) |
| 產品應用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 66kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ZNF675 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產品介紹 |
background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. TBZF (TRAF6-inhibitory zinc finger protein), also known as Zinc finger protein 675, is a 568 amino acid nuclear protein that contains one KRAB domain and fifteen C2H2-type zinc fingers. Through modulation of TRAF6 signaling activity and inhibition of RANK signaling, TBZF may play a role in osteoclast differentiation. TBZF is regulated during differentiation of human peripheral blood monocytes into osteoclasts and transfection of TBZF into RAW264.7 cells reduces RANK ligand-induced osteoclastogenesis. Function: May be involved in transcriptional regulation. May play a role during osteoclast differentiation by modulating TRAF6 signaling activity. Subunit: Interacts with TRAF6. Subcellular Location: Nucleus (Probable). Similarity: Contains 15 C2H2-type zinc fingers. brContains 1 KRAB domain. Database links: Entrez Gene: 171392 Human SwissProt: Q8TD23 Human Unigene: 264345 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 1、抗體溶解方法 | |
| 2、抗體修復方式 | |
| 3、常用試劑的配制 | |
| 4、免疫組化操作步驟 | |
| 5、免疫組化問題解答 | |
| 6、Western Blotting 操作步驟 | |
| 7、Western Blotting 問題解答 | |
| 8、關于肽鏈的設計 | |
| 9、多肽的溶解與保存 | |
| 10、酶標抗體效價測定程序 | |
