| 產(chǎn)品編號 | bs-16391R-PE-Cy5.5 |
| 英文名稱 | Rabbit Anti-ZXDC/PE-Cy5.5 Conjugated antibody |
| 中文名稱 | PE-Cy5.5標(biāo)記的鋅指蛋白ZXDC抗體 |
| 別 名 | SERH2790; UNQ2790; Zinc finger protein ZXDC; ZXD family zinc finger C; ZXD like zinc finger protein; ZXD-like zinc finger protein; Zxdc; ZXDC_HUMAN; ZXDL. |
| 規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 轉(zhuǎn)錄調(diào)節(jié)因子 鋅指蛋白 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Cow, Rabbit, Sheep, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 89kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ZXDC |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Zinc finger X-linked duplicated family member C (ZXDC) is an 858 amino acid protein belonging to the ZDX family. Localized to the nucleus, ZDXC is expressed at high levels in heart, kidney, liver and testis, with lower levels of expression in lung, muscle, placenta, small intestine and spleen. ZDXC, with ZDXA, forms a complex that binds to the class II trans-activator (CIITA). CIITA, like the X1-binding regulatory factor X (RFX) complex and the nuclear factor Y (NFY) complex, is a transcriptional co-factor that is necessary, but not sufficient, for major histocompatibility complex (MHC) class II gene transcription. ZXDC, by regulating CIITA function, activates the transcription of MHC genes. Function: Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes. Subcellular Location: Nucleus. Tissue Specificity: Expressed at high levels in heart, kidney, liver and testis, at moderate levels in brain and stomach, and at low levels in lung, muscle, placenta, small intestine and spleen. Similarity: Belongs to the ZXD family. Contains 10 C2H2-type zinc fingers. Database links: Entrez Gene: 79364 Human Entrez Gene: 80292 Mouse SwissProt: Q2QGD7 Human SwissProt: Q8C8V1 Mouse Unigene: 440049 Human Unigene: 711046 Human Unigene: 100116 Mouse Unigene: 473652 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
