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Rabbit Anti-ZXDC/AP Conjugated antibody (bs-16391R-AP)
訂購熱線:400-901-9800
訂購郵箱:sales@www.chomd.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@www.chomd.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-16391R-AP
英文名稱 Rabbit Anti-ZXDC/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標記的鋅指蛋白ZXDC抗體
別    名 SERH2790; UNQ2790; Zinc finger protein ZXDC; ZXD family zinc finger C; ZXD like zinc finger protein; ZXD-like zinc finger protein; Zxdc; ZXDC_HUMAN; ZXDL.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  轉錄調節因子  鋅指蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Cow, Rabbit, Sheep, )
產品應用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 89kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZXDC
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Zinc finger X-linked duplicated family member C (ZXDC) is an 858 amino acid protein belonging to the ZDX family. Localized to the nucleus, ZDXC is expressed at high levels in heart, kidney, liver and testis, with lower levels of expression in lung, muscle, placenta, small intestine and spleen. ZDXC, with ZDXA, forms a complex that binds to the class II trans-activator (CIITA). CIITA, like the X1-binding regulatory factor X (RFX) complex and the nuclear factor Y (NFY) complex, is a transcriptional co-factor that is necessary, but not sufficient, for major histocompatibility complex (MHC) class II gene transcription. ZXDC, by regulating CIITA function, activates the transcription of MHC genes.

Function:
Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes.

Subcellular Location:
Nucleus.

Tissue Specificity:
Expressed at high levels in heart, kidney, liver and testis, at moderate levels in brain and stomach, and at low levels in lung, muscle, placenta, small intestine and spleen.

Similarity:
Belongs to the ZXD family.
Contains 10 C2H2-type zinc fingers.

Database links:

Entrez Gene: 79364 Human

Entrez Gene: 80292 Mouse

Entrez Gene: 362399 Rat

SwissProt: Q2QGD7 Human

SwissProt: Q8C8V1 Mouse

Unigene: 440049 Human

Unigene: 711046 Human

Unigene: 100116 Mouse

Unigene: 473652 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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