| 產(chǎn)品編號 | bs-14638R-BF488 |
| 英文名稱 | Rabbit Anti-ESSPL/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的ESSPL蛋白抗體 |
| 別 名 | Epidermis specific serine protease like protein; Epidermis-specific serine protease-like protein; Gm1019; Protease serine 48; PRS48_HUMAN; PRSS48; Serine protease 48. |
| 規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 信號轉(zhuǎn)導(dǎo) 泛素 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 34kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ESSPL |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: ESPNL is a 1,005 amino acid protein that contains nine ANK repeats and exists as three alternatively spliced isoforms. The gene encoding ESPNL maps to human chromosome 2q37.3 and mouse chromosome 1 D. Chromosome 2 is the second largest human chromosome, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder known as Alstrom syndrome is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes. Subcellular Location: Secreted. Similarity: Belongs to the peptidase S1 family. Contains 1 peptidase S1 domain. Database links: Entrez Gene: 345062 Human SwissProt: Q7RTY5 Human Unigene: 651266 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
