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Rabbit Anti-NRK2/NEK4/APC Conjugated antibody (bs-19196R-APC)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-19196R-APC
英文名稱1 Rabbit Anti-NRK2/NEK4/APC Conjugated antibody
中文名稱 APC標記的絲氨酸/蘇氨酸蛋白激酶2抗體
別    名 EC 2.7.11.1; MGC33171; Never in mitosis A related kinase 4; Never in mitosis gene A related kinase 4; NIMA (never in mitosis gene a) related kinase 4; NIMA (never in mitosis gene a)-related expressed kinase 4; NIMA related kinase 4; NimA related protein kinase 4; NLK2; NRK2; NEK4_HUMAN; OTTHUMP00000213582; Pp12301; Serine/threonine kinase 2; Serine/threonine protein kinase 2; Serine/threonine protein kinase Nek4; Serine/threonine protein kinase NRK2; STK2.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  信號轉導  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 95kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NRK2/NEK4
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
NEK4 (NIMA related kinase 4) is a serine/threonine protein kinase related to the asperigillus NIMA (never in mitosis gene a) kinase. NEK4 is proposed to play a role in cell division. Highest expression in adult heart, followed by pancreas, skeletal muscle, brain, liver, kidney, lung and placenta. Present in most primary carcinomas. There are two named isoforms produced by alternative splicing.

Function:
Seems to act exclusively upon threonine residues.

Subcellular Location:
Nuclear

Tissue Specificity:
Highest expression in adult heart, followed by pancreas, skeletal muscle, brain, liver, kidney, lung and placenta. Present in most primary carcinomas.

Similarity:
Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.

Database links:

Entrez Gene: 6787 Human

Entrez Gene: 306252 Rat

Omim: 601959 Human

SwissProt: P51957 Human

Unigene: 631921 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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