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Rabbit Anti-PCLKC/AP Conjugated antibody (bs-13729R-AP)
訂購熱線:400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-13729R-AP
英文名稱1 Rabbit Anti-PCLKC/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標記的鈣粘蛋白LKC抗體
別    名 FLJ20124; FLJ20383; MGC163154; PC LKC; PC-LKC; Protocadherin LKC; CDHR2_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  信號轉導  細胞粘附分子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Pig, )
產品應用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 139kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PCLKC
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
PCLKC (Protocadherin LKC) belongs to the protocadherin gene family, a subgroup of the cadherin superfamily. It is predominantly expressed in liver, kidney and colon tissues, and has a role in contact inhibition at the lateral surface of epithelial cells. It is a candidate tumor suppressor.

Function:
Role in contact inhibition at the lateral surface of epithelial cells.

Subunit:
Interacts with MAST2.

Subcellular Location:
Apical cell membrane; Single-pass type I membrane protein. Cell junction. Note=Present at the cell junctions and the apical surface of cells. Colocalizes with actin at the microvilli-like structures which protrude from the apical surface.

Tissue Specificity:
Highly expressed in liver, kidney and colon. Moderately expressed in small intestine. Down-regulated in a number of liver and colon cancers.

Similarity:
Contains 9 cadherin domains.

Database links:

Entrez Gene: 54825 Human

SwissProt: Q9BYE9 Human

Unigene: 4205 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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