| 產(chǎn)品編號(hào) | bs-13580R-Cy5.5 |
| 英文名稱 | Rabbit Anti-ZBTB48/Cy5.5 Conjugated antibody |
| 中文名稱 | Cy5.5標(biāo)記的鋅指蛋白855抗體 |
| 別 名 | 0610011D15Rik; AI327031; GLI Kruppel family member HKR3; HKR3; Krueppel related zinc finger protein 3; Krueppel-related zinc finger protein 3; OTTMUSP00000031803; pp9964; Protein HKR3; RP23-445E20.3; ZBT48_HUMAN; ZBTB 48; Zbtb48; Zinc finger and BTB domain containing 48; Zinc finger and BTB domain containing protein 48; Zinc finger and BTB domain-containing protein 48; Zinc finger protein 855; ZNF855. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說(shuō) 明 書(shū) | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 轉(zhuǎn)錄調(diào)節(jié)因子 鋅指蛋白 表觀遺傳學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 77kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ZBTB48/ZNF855 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger and BTB domain-containing protein 48 (ZBTB48), also known as Kruppel-related zinc finger protein 3 or HKR3, is a 688 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZBTB48 is expressed in the adrenal gland and neuroblastoma cell lines. ZBTB48 contains a BTB domain, also known as a POZ domain, which inhibits DNA binding and mediates homotypic and heterotypic dimerization. Characteristics of the BTB domain suggest that ZBTB48 functions as a transcription regulator. Function: Binds to and regulates the J and/or S elements in MHC II promoter. Subcellular Location: Nucleus. Tissue Specificity: Detected in adrenal gland and neuroblastoma. Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 1 BTB (POZ) domain. Contains 11 C2H2-type zinc fingers. Database links: Entrez Gene: 3104 Human Entrez Gene: 100090 Mouse Omim: 165270 Human SwissProt: P10074 Human SwissProt: Q1H9T6 Mouse Unigene: 502330 Human Unigene: 24661 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
