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Rabbit Anti-ZBTB25/BF647 Conjugated antibody (bs-13568R-BF647)
訂購熱線:400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-13568R-BF647
英文名稱 Rabbit Anti-ZBTB25/BF647 Conjugated antibody
中文名稱 BF647標記的鋅指蛋白46抗體
別    名 ZBT25_HUMAN; ZBTB25; Zinc finger and BTB domain-containing protein 25; Zinc finger protein 46; Zinc finger protein KUP.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  信號轉導  鋅指蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Horse, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 49kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZBTB25/ZNF46
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger and BTB domain-containing protein 25 (ZBTB25), also known as ZNF46 or KUP, is a 435 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus and expressed mainly in hematopoietic cells and testis, ZBTB25 contains a BTB domain, also known as a POZ domain, which inhibits DNA binding and mediates homotypic and heterotypic dimerization. Characteristics of the BTB domain suggest that ZBTB25 functions as a transcription regulator.

Function:
May be involved in transcriptional regulation.

Subcellular Location:
Nucleus.

Tissue Specificity:
Expressed mainly in hematopoietic cells and testis.

Similarity:
Contains 1 BTB (POZ) domain.
Contains 2 C2H2-type zinc fingers.

Database links:

Entrez Gene: 7597 Human

Omim: 194541 Human

SwissProt: P24278 Human

Unigene: 654571 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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