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Rabbit Anti-AMBN/Gold Conjugated antibody (bs-12467R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-12467R-Gold
英文名稱1 Rabbit Anti-AMBN/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的釉基質(zhì)蛋白抗體
別    名 AMBN; AMBN_HUMAN; Ameloblastin (enamel matrix protein); Ameloblastin.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞骨架  細(xì)胞外基質(zhì)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 45kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human AMBN
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
Dental enamel is a highly mineralized tissue with most of its volume occupied by large, highly organized, hydroxyapatite crystals. This structure is thought to be controlled through the interaction of many organic matrix molecules including amelogenin, ameloblastin, enamelin, tuftelin and several other enzymes. All of these secreted proteins are involved in the mineralization and enamel matrix formation in developing tooth enamel. Ameloblastin (AMBN), which localizes to the extracellular matrix, is an ameloblast-specific protein. It is detected in the sheath space between rod-interrod enamel and at the Tomes processes of secretory ameloblasts. Defects in the gene encoding for ameloblastin, AMBN, can be seen in patients with ameloblastomas.

Function:
Involved in the mineralization and structural organization of enamel.

Subcellular Location:
Secreted > extracellular space > extracellular matrix.

Tissue Specificity:
Ameloblast-specific. Located at the Tomes processes of secretory ameloblasts and in the sheath space between rod-interrod enamel.

Similarity:
Belongs to the ameloblastin family.

Database links:

Entrez Gene: 258 Human

Omim: 601259 Human

SwissProt: Q9NP70 Human

Unigene: 272396 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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