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Rabbit Anti-COX8C/BF647 Conjugated antibody (bs-14017R-BF647)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-14017R-BF647
英文名稱1 Rabbit Anti-COX8C/BF647 Conjugated antibody
中文名稱 BF647標記的細胞色素C氧化酶蛋白8C抗體
別    名 COX VIII-3; COX8-3; Cox8c; COX8C_HUMAN; cytochrome c oxidase polypeptide 8; Cytochrome c oxidase polypeptide 8 isoform 3; cytochrome c oxidase polypeptide VIII; Cytochrome c oxidase polypeptide VIII isoform 3; Cytochrome c oxidase subunit 8-3; Cytochrome c oxidase subunit 8C; Cytochrome c oxidase subunit 8C, mitochondrial; cytochrome c oxidase subunit VIII; cytochrome c oxidase subunit VIIIC; mitochondrial.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  新陳代謝  線粒體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 4.8kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human COX8C
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water and ATP. The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some of which are nuclear. The COX8 (cytochrome c oxidase subunit VIII) subunits are nuclear and have muscle and non-muscle-specific isoforms. COX8 exists as three isoforms: COX8a, a liver and heart isoform, Cox8b, a heart-specific isoform, and Cox8c, whose expression pattern has yet to be elucidated. All three Cox8 isoforms exists as components of the COX complex and play an important role in electron transport.

Function:
This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.

Subcellular Location:
Mitochondrion inner membrane.

Tissue Specificity:
It is not yet known where COX8C is expressed.

Similarity:
Belongs to the cytochrome c oxidase VIII family.

Database links:

Entrez Gene: 341947 Human

Entrez Gene: 75483 Mouse

Entrez Gene: 360229 Rat

SwissProt: Q7Z4L0 Human

SwissProt: A6H666 Mouse

SwissProt: Q7TNN2 Rat

Unigene: 666459 Human

Unigene: 660 Mouse

Unigene: 98192 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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