| 產品編號 | bs-11971R-BF488 |
| 英文名稱 | Rabbit Anti-RAMP2/BF488 Conjugated antibody |
| 中文名稱 | BF488標記的受體活性修飾蛋白2抗體 |
| 別 名 | Calcitonin receptor like receptor activity modifying protein 2; CRLR activity modifying protein 2; OTTMUSP00000002615; OTTMUSP00000037624; Receptor (calcitonin) activity modifying protein 2; Receptor activity modifying protein 2; Receptor activity modifying protein 2 isoform; RP23-281C18.6; RAMP2_HUMAN. |
| 規格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領域 | 腫瘤 細胞生物 信號轉導 生長因子和激素 細胞膜受體 G蛋白偶聯受體 G蛋白信號 細胞膜蛋白 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應 | (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, ) |
| 產品應用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 15kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human RAMP2 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產品介紹 |
background: The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP2) protein, CRLR functions as an adrenomedullin receptor. The RAMP2 protein is involved in core glycosylation and transportation of adrenomedullin receptor to the cell surface. Function: RAMP2 (Receptor activity-modifying protein 2) transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. RAMP2 acts as a receptor for adrenomedullin (AM) together with CALCRL. Co-expression of Receptor activity-modifying protein 2 (RAMP2) with the calcitonin-receptor-like-receptor (CRLR) results in the production of a functional adrenomedullin (ADM) receptor. RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor. RAMP2 is a heterodimer of CALCRL and RAMP2. RAMP2 is strongly expressed in lung, breast, immune system and fetal tissues. RAMP2 belongs to the RAMP family. Subunit: Heterodimer of CALCRL and RAMP2 Subcellular Location: Cell Membrane; Single-pass type I membrane protein Tissue Specificity: Strongly expressed in lung, breast, immune system and fetal tissues. Similarity: Belongs to the RAMP family. Database links: UniProtKB/Swiss-Prot: O60895.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 1、抗體溶解方法 | |
| 2、抗體修復方式 | |
| 3、常用試劑的配制 | |
| 4、免疫組化操作步驟 | |
| 5、免疫組化問題解答 | |
| 6、Western Blotting 操作步驟 | |
| 7、Western Blotting 問題解答 | |
| 8、關于肽鏈的設計 | |
| 9、多肽的溶解與保存 | |
| 10、酶標抗體效價測定程序 | |
