亚洲中文字幕特级毛片-亚洲制服丝袜中文字幕-亚洲制服丝袜在线观看-亚洲制服欧美自拍另类-免费一级黄色-免费一级国产生活片

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
无码免费一区二区三区免费播放,亚洲一区二区三区在线网站,香港三日本8a三级少妇三级99
Rabbit Anti-LIN7C/FITC Conjugated antibody (bs-11872R-FITC)
訂購熱線:400-901-9800
訂購郵箱:sales@www.chomd.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@www.chomd.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-11872R-FITC
英文名稱1 Rabbit Anti-LIN7C/FITC Conjugated antibody
中文名稱 FITC標(biāo)記的LIN7C蛋白抗體
別    名 LIN 7 C; Lin 7 homolog C (C. elegans); LIN 7 protein 3; LIN 7C; LIN7 protein 3; MALS 3; MALS3; Mammalian lin seven protein 3; Veli 3 protein; VELI3; Vertebrate lin 7 homolog 3; LIN7C_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞膜受體  細(xì)胞粘附分子  結(jié)合蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Zebrafish, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 22kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LIN7C
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Velis are a family of small synaptic proteins that interact with other proteins at the post-synaptic density (PSD) of neuronal synapses. Velis contain the PDZ motif involved in recruiting cell adhesion molecules, receptors, and channels. Veli1 (also designated Lin-7A and MALS-1), Veli2 (also designated Lin-7B and MALS-2), and Veli3 (also designated Lin-7C and MALS-3) are mammalian homologs of C. elegans LIN-7. Veli proteins are ubiquitously expressed with high expression in brain, liver, and testis. Velis are localized at the synaptic junctions in neurons. Velis bind to CASK, a neurexin-binding protein highly concentrated in synapses, and Mint1, a binding partner with a vesicle trafficking protein.

Function:
LIN7C plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. It forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. LIN7C ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. It is also required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.

Subunit:
Forms two exclusive ternary complexes with CASK and APBA1 or CASKIN1 (By similarity). Can also interact with other modular proteins containing protein-protein interaction domains like MPP5, MPP6, MPP7, DLG1, DLG2 and DLG3 through its L27 domain. Interacts with DLG4 and GRIN2B as well as CDH1 and CTNNB1, the channels KCNJ12/Kir2.2, KCNJ4/Kir2.3 and probably KCNJ2/Kir2.1 and SLC6A12/BGT-1 via its PDZ domain. The association of LIN7A with cadherin and beta-catenin is calcium-dependent, occurs at synaptic junctions and requires the actin cytoskeleton. Interacts with EGFR, ERBB2, ERBB3 and ERBB4 with both PDZ and KID domains. Associates with KIF17 via APBA1. Interacts with HTR4 (By similarity). Forms a tripartite complex composed of DLG1, MPP7 and LIN7 (LIN7A or LIN7C). Interacts with MAPK12

Subcellular Location:
Cell membrane. Peripheral membrane protein. Basolateral cell membrane. Cell junction. Enriched in synaptosomes and at epithelial cell-cell junctions. Mainly basolateral in renal epithelial cells.

Similarity:
Belongs to the lin-7 family.
Contains 1 L27 domain.
Contains 1 PDZ (DHR) domain.

Database links:
UniProtKB/Swiss-Prot: Q9NUP9.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.www.chomd.com.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
主站蜘蛛池模板: 欧美乱大交XXXXX潮喷P10| 老熟妇又粗又大,无码日韩人妻精| 久久综合婷婷丁香五月天| 精品国产亚洲一区二区三区,中文字字幕 | 久久精品成人无码观看免 | 日本中文字幕有码网红小辣椒白浆| 久久精品一区二区三区AⅤ 鲁丝一区 | 中文字幕123区动漫制服丝袜| 亚洲 中文字幕 人妻制服| 久久久亚洲AV无码精油二区| 工口污久久婷国产精品网站| 丰满少妇大力进入动态视频 | 国产又爽又黄又不遮挡视频,丰满又黄又爽少妇 | 亚洲欧洲日韩国产妹妹 | 草莓视频在线观看官方最新版| 国产自啪精品视频网站丝袜高跟 | 精品无码AV一区二区三区_别拔出来| 久久精品99久久香蕉国产一区| 99久久国产宗和精品1上映[原创]护士| 成人免费久久久66| 亚洲 国产 图片 抖音| 国产在线精品一区二区不卡了奶牛| 在线看福利中文影院视频| 久久婷婷五月综合色精品| 欧美精品中文字幕 | 国产vr一区二区在线观看视频| 亚洲精品乱码久久久久久自慰人妖| 亚洲乱码日产精品bd在线观看| 久久精品系列偷拍女人屁股屁股| 自拍视频在线观看一区二区不卡vip人口 | 亚洲精品国产高清在线观看不卡|99| 香蕉成人伊视频在线观看免| 精品97国产免费人成视频|中文h综| 在线观看视频vivo新出的nex | 亚洲中文婷婷48| 国产一区二区内射最近更新漫画| 亚洲欧洲精品成人久久曰影片亚洲| 国产一区二区三区在线看网 | 一级做a爰片性色毛片免费网站少| 精品免费久久久久久久久少妇 | 午夜精品久久久久久中宇,亚洲一区二区三区无码国产 | 亚洲黄色在线观看网站纯肉|