亚洲中文字幕特级毛片-亚洲制服丝袜中文字幕-亚洲制服丝袜在线观看-亚洲制服欧美自拍另类-免费一级黄色-免费一级国产生活片

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
国产精品内射久久久久欢欢,亚洲av成人片色在线观看高潮,天天夜碰日日摸日日澡
Rabbit Anti-CD40L/RBITC Conjugated antibody (bs-1286R-RBITC)
訂購熱線:400-901-9800
訂購郵箱:sales@www.chomd.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@www.chomd.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-1286R-RBITC
英文名稱1 Rabbit Anti-CD40L/RBITC Conjugated antibody
中文名稱 羅丹明(RBITC)標(biāo)記的CD40L抗體
別    名 TNFSF5; CD 154; CD154; CD 40L; CD154; CD154 antigen; CD40 homologue; CD40 ligand; CD40LG; gp39; hCD40L; HIGM1; Hyper IgM syndrome; IGM; IMD3; Ly62; T B cell activating molecule; T cell antigen GP39; TBAM; TNF related activation protein; TNF superfamily member 5; Tnfsf5; TRAP; Tumor necrosis factor (ligand) superfamily member 5.   
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞凋亡  細(xì)胞膜受體  細(xì)胞表面分子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Rat, 
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 29kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CD40L
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
CD40 ligand (CD40L) is a 33 kDa type II membrane glycoprotein expressed mainly on the cell surface of activated T lymphocytes, but also exists as a soluble form extracellularly. CD40L is the ligand for CD40, a member of the TNF superfamily, which is expressed on the cell surface of B cells, macrophages/monocytes, dendritic cells, vascular endothelial cells, and epithelial cells. CD40L plays an important role in B cell proliferation, antibody class switching, modulation of apoptosis in the germinal center through interaction with B cells expressing CD40, and activation of CD4+ T cells. Mutation within the CD40L gene is linked to hyper IgM syndrome, an X linked immunodeficiency disease that is characterized by elevated level of serum IgM and decreased level of other isotypes.

Function:
Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching. Release of soluble CD40L from platelets is partially regulated by GP IIb/IIIa, actin polymerization, and an matrix metalloproteinases (MMP) inhibitor-sensitive pathway.

Subcellular Location:
Secreted and Cell membrane.

Tissue Specificity:
Specifically expressed on activated CD4+ T-lymphocytes.

DISEASE:
Defects in CD40LG are the cause of X-linked immunodeficiency with hyper-IgM type 1 (HIGM1) [MIM:308230]; also known as X-linked hyper IgM syndrome (XHIM). HIGM1 is an immunoglobulin isotype switch defect characterized by elevated concentrations of serum IgM and decreased amounts of all other isotypes. Affected males present at an early age (usually within the first year of life) recurrent bacterial and opportunistic infections, including Pneumocystis carinii pneumonia and intractable diarrhea due to cryptosporidium infection. Despite substitution treatment with intravenous immunoglobulin, the overall prognosis is rather poor, with a death rate of about 10% before adolescence.

Similarity:
Belongs to the tumor necrosis factor family.

Database links:

Entrez Gene: 959 Human

Entrez Gene: 21947 Mouse

Entrez Gene: 84349 Rat

Omim: 300386 Human

SwissProt: P29965 Human

SwissProt: P27548 Mouse

SwissProt: Q9Z2V2 Rat

Unigene: 592244 Human

Unigene: 4861 Mouse

Unigene: 44218 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

CD40L也是T細(xì)胞活化的重要輔助刺激通路,不僅在調(diào)節(jié)T細(xì)胞免疫反應(yīng)中起關(guān)鍵作用,而且也在B細(xì)胞的活化、增殖、分化、抗體的分泌起重要作用。主要表達(dá)在B細(xì)胞,有抗凋亡和促生長、分化的作用。
版權(quán)所有 2004-2026 www.www.chomd.com.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
主站蜘蛛池模板: 国产国语对白AA片| 亚洲一本一道最新地址| 日本一本二本三本在线| 久久久精品人妻一区二区三区四区金瓶梅 | 全免费A级毛片免费看无码| 激情综合五月激情四月 | 精品成人免费自拍视频网站| 99国产红豆一区二区三区四区| 亚洲精品狼友在线播放 网站亚洲精品无码| 拍拍拍无挡视频免费观看1000字 | 国产激情视频在线观看首页| 亚洲中文婷婷888| 久久久青青熟妇一区| 中文字幕亚洲综合精品一区99精品久久中文字幕日韩精品 | 国产一二三区在线观看视频在线观看| 中文字幕亚洲情99在线,野花社区www视| 午夜精品久久久久成人_色综合久久一| 狠狠亚洲狠狠欧洲熟女| 一级毛片免费不卡直播观看性色所有全部爆乳粗大 | 中文在线观看免费网站毛片| 人妻91无码色偷偷色噜噜噜久草电影网| 国产成人午夜精华液免费| 亚洲精品国产自在久久出水,精品一区二区三区四区 | 天堂8在线天堂资源b+t | 无码人妻AV免费一区二区三区_久久先 | 中文字幕精品一区二区精品5566 | 国产91精品一区二区绿帽 | 日本视频一本道电车| 91精品国产综合久久精品,亚洲精品国产专区9 | 免费精品一区二区三区第35集| 91午夜精品亚洲一区二区三区密桃 | 日韩人妻中文在线视频免费视频 | 影音先锋5566中文源资源| 久久久久久久久毛片精品火炮美女| 3344成年视频免费观看| 久久高清内射无套同性恋 | 亚洲六月丁香色婷婷综合久久| 国产男女一区二区裸体插爱| 少妇又紧又粗又爽的视频| 中文字幕色av一区二区三区在线| 精品日日骚视频一区二区|