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Rabbit Anti-TCPTP/PTPIP51/BF488 Conjugated antibody (bs-5719R-BF488)
訂購熱線:400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-5719R-BF488
英文名稱 Rabbit Anti-TCPTP/PTPIP51/BF488 Conjugated antibody
中文名稱 BF488標記的蛋白酪氨酸磷酸酶相互作用蛋白51抗體
別    名 Cerebral protein 10; Family with sequence similarity 82 member C; hRMD 3; Microtubule associated protein; Protein FAM82A2; Protein FAM82C; Protein tyrosine phosphatase interacting protein 51; PTPIP51; Regulator of microtubule dynamics 3; Regulator of microtubule dynamics protein 3; RMD 3; RMD3; TCPTP interacting protein 51; RMD3_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  免疫學  細胞周期蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 52kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PTPIP51/FAM82A2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
FAM82A2, or family with sequence similarity 82, member C, may participate in differentiation and apoptosis of keratinocytes. Overexpression of FAM82A2 induces apoptosis.

Function:
Involved in cellular calcium homeostasis regulation. May participate in differentiation and apoptosis of keratinocytes. Overexpression induces apoptosis.

Subunit:
Interacts with PTPN2. Interacts with microtubules. Interacts with VAPB.

Subcellular Location:
Mitochondrion membrane; Single-pass membrane protein. Mitochondrion outer membrane. Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=In interphase localizes in the cytoplasm, and during mitosis localizes to the spindle microtubules and spindle poles.

Tissue Specificity:
Present at high level in epidermis and seminiferous epithelium: while basal cells in the epidermis and spermatogonia show no perceptible amount, keratinocytes of suprabasal layers and differentiating first-order spermatocytes up to spermatids exhibit high expression. In skeletal muscle, its presence is restricted to fibers of the fast twitch type. In surface epithelia containing ciliated cells, it is associated with the microtubular structures responsible for ciliary movement. Also present in specific structures of the central nervous system such as neurons of the hippocampal region, ganglion cells of the autonomic nervous system, and axons of the peripheral nervous system (at protein level). Widely expressed.

Similarity:
Belongs to the RMDN family.

Database links:

Entrez Gene: 5771 Human

Entrez Gene: 19255 Mouse

Entrez Gene: 117063 Rat

Omim: 176887 Human

SwissProt: P17706 Human

SwissProt: Q06180 Mouse

SwissProt: P35233 Rat

Unigene: 654527 Human

Unigene: 663373 Human

Unigene: 260433 Mouse

Unigene: 33497 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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