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Rabbit Anti-phospho-JunD (Ser255)/PE-Cy5 Conjugated antibody (bs-5466R-PE-Cy5)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-5466R-PE-Cy5
英文名稱 Rabbit Anti-phospho-JunD (Ser255)/PE-Cy5 Conjugated antibody
中文名稱 PE-Cy5標(biāo)記的磷酸化活化蛋白激酶D抗體
別    名 JunD (phospho S255); JunD (Phospho Ser255); Transcription factor jun-D; jun D proto-oncogene; JUND1; AP-1; JUND; JUND1; MGC6245; MGC72300; AP 1; AP1; jun D proto oncogene; JunD FL isoform; JUND_HUMAN; Transcription factor jun D; transcription factor jun-D isoform JunD-FL; Jun-like transcription factor; pfam03957.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
產(chǎn)品類型 磷酸化抗體 
研究領(lǐng)域 腫瘤  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Chicken, Dog, Cow, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 38kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human JunD around the phosphorylation site of Ser255
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The cJun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus vjun oncogene. JunB and JunD have been shown to be almost identical to cJun in their C terminal regions, which are involved in dimerization and DNA binding, whereas their N terminal domains, which are involved in transcriptional activation, diverge. JunB is a transcription factor involved in regulating gene activity following the primary growth factor response. It binds to the DNA sequence 5'-TGA[CG]TCA-3'.

Function:
Transcription factor binding AP-1 sites.

Subunit:
Binds DNA as a dimer (By similarity). Interacts with MEN1; this interaction represses transcriptional activation.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the bZIP family. Jun subfamily.
Contains 1 bZIP (basic-leucine zipper) domain.

Database links:

Entrez Gene: 3727 Human

Entrez Gene: 16478 Mouse

Entrez Gene: 24518 Rat

Omim: 165162 Human

SwissProt: P17535 Human

SwissProt: P15066 Mouse

SwissProt: P52909 Rat

Unigene: 2780 Human

Unigene: 419851 Mouse

Unigene: 46225 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Jun-D屬于轉(zhuǎn)錄因子AP-1家族(Jun蛋白家族包括c-Jun、JunB和JunD)
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