| 產(chǎn)品編號 | bs-0098R-PE |
| 英文名稱1 | Rabbit Anti-GIP/PE Conjugated antibody |
| 中文名稱 | PE標(biāo)記的胃泌素抑制肽抗體 |
| 別 名 | Gastric Inhibitory polypeptide; Gastric inhibitory polypeptide precursor; GIP; Glucose dependent insulinotropic polypeptide; Gastric Inhibitory Peptide; GIP_HUMAN; Glucose-dependent insulinotropic polypeptide; Incretin hormone. |
| 規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 信號轉(zhuǎn)導(dǎo) 生長因子和激素 轉(zhuǎn)錄調(diào)節(jié)因子 糖尿病 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse, (predicted: Human, Rat, Pig, Cow, ) |
| 產(chǎn)品應(yīng)用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 5/17kDakDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GIP |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: GIP (Gastric Inhibitory polypeptide ) belongs to the glucagon superfamily. The encoded protein is important in maintaining glucose homeostasis as it is a potent stimulator of insulin secretion from pancreatic beta-cells following food ingestion and nutrient absorption. This gene stimulates insulin secretion via its G protein-coupled receptor activation of adenylyl cyclase and other signal transduction pathways. It is a relatively poor inhibitor of gastric acid secretion. Mature GIP is a highly conserved 42 amino acid polypeptide belonging to the glucagon family. GIP is highly expressed as a pre-pro-protein in the duodenum and the jejunum. The mature secreted polypeptide acts as a potent stimulator of insulin secretion and a poor inhibitor of gastric acid secretion. Function: Potent stimulator of insulin secretion and relatively poor inhibitor of gastric acid secretion. Subcellular Location: Secreted. Similarity: Belongs to the glucagon family. Database links: Entrez Gene: 2695 Human Omim: 137240 Human SwissProt: P09681 Human Unigene: 1454 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 胃泌素抑制肽（GIP）是胃腸道的一種由42個(gè)氨基酸組成的多肽激素，又稱為葡萄糖依賴性促胰島素多肽（glucose-dependent insulinotropic peptide，GIP）他強(qiáng)烈抑制胃分泌和運(yùn)動，也可調(diào)節(jié)胰島素的釋放。GIP屬于Glucagon家族成員。 |
