亚洲中文字幕特级毛片-亚洲制服丝袜中文字幕-亚洲制服丝袜在线观看-亚洲制服欧美自拍另类-免费一级黄色-免费一级国产生活片

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
青娱乐在线免费视频,久久精品国产一区二区电影,爱情岛永久地址www成人
Rabbit Anti-phospho-PKA beta(Ser339)/PE-Cy7 Conjugated antibody (bs-4024R-PE-Cy7)
訂購熱線:400-901-9800
訂購郵箱:sales@www.chomd.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@www.chomd.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-4024R-PE-Cy7
英文名稱 Rabbit Anti-phospho-PKA beta(Ser339)/PE-Cy7 Conjugated antibody
中文名稱 PE-Cy7標(biāo)記的磷酸化蛋白激酶Aβ抗體
別    名 PRKACB (phospho Ser339); PRKACB (phospho S339); PRKACA (phospho Ser339); PRKACA (phospho S339); PKA alpha + beta (catalytic subunits) (phospho S339); PKA alpha + beta (phospho S339); PKA C beta; PKACB; PRKACB; Protein kinase cAMP dependent catalytic beta; cAMP-dependent protein kinase catalytic subunit beta; KAPCB_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
產(chǎn)品類型 磷酸化抗體 
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 40kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human PKA beta around the phosphorylation site of Ser339
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]

Function:
Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis.

Subunit:
A number of inactive tetrameric holoenzymes are produced by the combination of homo- or heterodimers of the different regulatory subunits associated with two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. The cAMP-dependent protein kinase catalytic subunit binds PJA2 (By similarity).

Subcellular Location:
Cytoplasm. Cell membrane. Nucleus (By similarity). Note=Translocates into the nucleus (monomeric catalytic subunit) (By similarity). The inactive holoenzyme is found in the cytoplasm (By similarity).

Tissue Specificity:
Isoform 1 is most abundant in the brain, with low level expression in kidney. Isoform 2 is predominantly expressed in thymus, spleen and kidney. Isoform 3 and isoform 4 are only expressed in the brain.

Post-translational modifications:
Asn-3 is partially deaminated to Asp giving rise to 2 major isoelectric variants, called CB and CA respectively (By similarity).

Similarity:
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.
Contains 1 AGC-kinase C-terminal domain.
Contains 1 protein kinase domain.

Database links:

Entrez Gene: 282322 Cow

Entrez Gene: 282323 Cow

Entrez Gene: 5566 Human

Entrez Gene: 5567 Human

Entrez Gene: 18747 Mouse

Entrez Gene: 18749 Mouse

Entrez Gene: 25636 Rat

Omim: 176892 Human

Omim: 601639 Human

SwissProt: P00517 Cow

SwissProt: P17612 Human

SwissProt: P22694 Human

SwissProt: P05132 Mouse

SwissProt: P05206 Mouse

SwissProt: P27791 Rat

Unigene: 391 Cow

Unigene: 4420 Cow

Unigene: 487325 Human

Unigene: 631630 Human

Unigene: 16766 Mouse

Unigene: 19111 Mouse

Unigene: 103828 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.www.chomd.com.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
主站蜘蛛池模板: mm131亚洲精品美女自拍| 精品无码成人片一区二区78 | 99久久久久久久无码| 又色又爽又黄的视频网站_欧美顶级牲交片 | 天堂8在线天堂资源在线,美丽姑娘在线观看完整版中文 | 久久精品人人爽人人爽精品| 国产69精品久久久久99尤物视频| 在线精品卡1卡二卡3卡四卡| 少妇被又大又粗又爽毛片久久黑人按摩 | 国产美女久久精品香蕉精品| 一级毛片免费不卡直播观看性色所有全部爆乳粗大| 亚洲五月六月丁香激情 91大神| 久日AV在线播放网址导航| 草莓视频在线观看国产免费专区 | 无码人妻一区二区三区在线视频后妈裙| 精品少妇人妻av一区二区软件下载 | 午夜天堂一区人妻特级做A爱片毛片免费| 久久av午夜色情亚洲剧场| 中文字幕内射无码视频在线观看 | 91亚洲国产成人久久精品蜜臀 作者 | 樱桃视频成人AV| 久久精品国产成人98| 91久久午夜无码鲁丝片久久人妻| 色综合久久久久久久久五月_无| 国产免费高清69式视频在线观看| 亚洲国产成人精品电影女久久久 | 亚洲精品一区二区三区在线| 精品无码国产自产拍在线观看软件老太太拍拍拍 | 亚洲国产一区在线2016| 国产免费一区二区三区在线观看_| 一区二区三区四区在线播放Av | 中文字幕无码久久久久页码视频| 日本岛国片免费| 中文字幕在线视频网站99在| 久久久久久亚洲中文字幕不卡| 一本精品99久久精品中文77久久97超...| 久久久无码AV精品亚洲油麻菜| 亚洲一区二区三区91麻豆| 国产美女视频免费观看的网站大全| 亚洲AV色香蕉一区二区三区老师| 非洲无码AAA视频|