| 產(chǎn)品編號 | bs-3937R-BF488 |
| 英文名稱 | Rabbit Anti-ETFB/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的電子轉(zhuǎn)移黃素蛋白β肽/黃素蛋白抗體 |
| 別 名 | Flavoprotein; Beta ETF; FP; Beta-ETF; Electron transfer flavoprotein beta polypeptide; Electron transfer flavoprotein beta subunit; Electron transfer flavoprotein subunit beta; Electron transferring flavoprotein beta polypeptide; etfB; ETFB_HUMAN; FP585; MADD. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 腫瘤 細胞生物 免疫學(xué) 信號轉(zhuǎn)導(dǎo) 轉(zhuǎn)錄調(diào)節(jié)因子 線粒體 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Pig, Cow, ) |
| 產(chǎn)品應(yīng)用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 28kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ETFB |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase. Function: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). Subunit: Heterodimer of an alpha and a beta subunit. Subcellular Location: Mitochondrion matrix. Tissue Specificity: Abundant in liver, heart and skeletal muscle. A weak expression is seen in the brain, placenta, lung, kidney and pancreas. DISEASE: Defects in ETFB are the cause of glutaric aciduria type 2B (GA2B) [MIM:231680]. GA2B is an autosomal recessively inherited disorder of fatty acid, amino acid, and choline metabolism. It is characterized by multiple acyl-CoA dehydrogenase deficiencies resulting in large excretion not only of glutaric acid, but also of lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Similarity: Belongs to the ETF beta-subunit/fixA family. Database links: UniProtKB/Swiss-Prot: P38117.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 黃素蛋白是由一條多肽結(jié)合1個輔基組成的酶類，不是脂溶性。結(jié)合的輔基可以是FAD或FMN,它們是維生素B2的衍生物，每個輔基能夠接受和提供兩個質(zhì)子和電子。線粒體中的黃素蛋白主要是電子傳遞鏈中NADH脫氫酶和TCA循環(huán)中的琥珀酸脫氫酶。 |
