亚洲中文字幕特级毛片-亚洲制服丝袜中文字幕-亚洲制服丝袜在线观看-亚洲制服欧美自拍另类-免费一级黄色-免费一级国产生活片

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
国产成人av一区二区三区在线,国产成人mv在线播放,午夜男女爽爽影院网站
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-Phospho-eNOS (Thr113)/PE Conjugated antibody (bs-3589R-PE)
訂購熱線:400-901-9800
訂購郵箱:sales@www.chomd.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@www.chomd.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-3589R-PE
英文名稱 Rabbit Anti-Phospho-eNOS (Thr113)/PE Conjugated antibody
中文名稱 PE標記的磷酸化一氧化氮合成酶3(內(nèi)皮型)抗體
別    名 eNOS (phospho S113); p-eNOS (phospho S113); eNOS (Phospho-Ser113); cNOS; eNOS; Constitutive NOS; EC NOS; ecNOS; Endothelial nitric oxidase synthase; Endothelial nitric oxide synthase; Endothelial nitric oxide synthase 3; Endothelial NOS; Nitric oxide synthase 3 (endothelial cell); Nitric oxide synthase 3; Nitric oxide synthase 3 endothelial cell; Nitric oxide synthase endothelial; nitric oxide synthase, endothelial; NOS 3; NOS III; NOS type III; NOS3; NOSIII; NOS3_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
產(chǎn)品類型 磷酸化抗體 
研究領(lǐng)域 免疫學(xué)  神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  細胞凋亡  轉(zhuǎn)錄調(diào)節(jié)因子  合成與降解  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Mouse, Rat, Dog, Rabbit, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 133kDa
細胞定位 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from mouse eNOS around the phosphorylation site of Ser113
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
eNOS is a calcium/calmodulin dependent enzyme which undergoes several post translational modifications, including acylation with myristate and palmitate, and phosphorylation on numerous residues. As with the other members of the NOS family, eNOS derives the diffusible multifunctional second messenger NO from L arginine through a series of reactions in which L citrulline is an intermediate. eNOS plays an important role in controlling vascular tone, platelet aggregation, and cardiac myocyte function.

Function:
Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.
Isoform eNOS13C: Lacks eNOS activity, dominant-negative form that may down-regulate eNOS activity by forming heterodimers with isoform 1.

Subunit:
Homodimer. Interacts with NOSIP and NOSTRIN.

Subcellular Location:
Cell membrane. Membrane, caveola. Cytoplasm, cytoskeleton. Golgi apparatus. Note=Specifically associates with actin cytoskeleton in the G2 phase of the cell cycle; which is favored by interaction with NOSIP and results in a reduced enzymatic activity.

Tissue Specificity:
Platelets, placenta, liver and kidney.

Post-translational modifications:
Phosphorylation by AMPK at Ser-1177 in the presence of Ca(2+)-calmodulin (CaM) activates activity. In absence of Ca(2+)-calmodulin, AMPK also phosphorylates Thr-495, resulting in inhibition of activity. Phosphorylation of Ser-114 by CDK5 reduces activity.

Similarity:
Belongs to the NOS family.
Contains 1 FAD-binding FR-type domain.
Contains 1 flavodoxin-like domain.

Database links:

Entrez Gene: 287024 Cow

Entrez Gene: 403784 Dog

Entrez Gene: 4846 Human

Entrez Gene: 18127 Mouse

Entrez Gene: 397557 Pig

Entrez Gene: 24600 Rat

Omim: 163729 Human

SwissProt: P29473 Cow

 



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

催化生物體內(nèi)一氧化氮(NO)生成的酶。分神經(jīng)型一氧化氮合成的酶(nNOS or NOS-1)、誘導(dǎo)型一氧化氮合成的酶(iNOS or NOS-2)、內(nèi)皮型一氧化氮合成的酶(eNOS or NOS-3)。此抗體識別分子量為135kDa的內(nèi)皮型一氧化氮合成的酶。
版權(quán)所有 2004-2026 www.www.chomd.com.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: eeuss影院在线观看高清| 久久久久久久久久969| 成年网站免费入口在线观看AV| 岛国无码在线视频播放网页 | AV一二三四区AV| 亚洲综合无码一区二区三区天堂人 婷婷 | 在线观看动漫aV游戏| 丝袜精品一区二区视频| 精品久久久久久久久中文字幕_亚洲精品 | 久久亚洲综合网区| 人妻キメちゃいました| 精品人妻一区二区三区四区中文字幕| 国产69熟妇xXX| 亚洲天码不卡熟女| 久久视热这只是精品222| 潮喷失禁大喷水无码sihu| 亚洲精品无码久久千人斩探花|国产综合| 色婷婷五月中文字幕泽村玲子 | 亚洲精品尤物在线自然 | 亚洲精品白浆高清久久久久久人妖怪| 内射人妻少妇无码一本一道九九r片| 国产一区二区三区影院综合 | 日日狠狠久久偷偷色综合昆山| 国产一卡二卡三卡四卡小说| 一本一道AⅤ波多野极衣| 另类TS人妖一区二区三区| av中文字幕网站有码| 少妇被又大又粗又爽毛片久久黑人茄子视频 | 中文字幕人妻字幕乱码中文乱码 | 丰满人爽人妻A片二区动漫君冢日向| 一区二区三区在线播放视频软件下载 | 在线无码精品秘?| 久久天天躁狠狠躁夜夜网站阿朱3p有完整| 国产99视频精品免视看4| 亚洲AV之男人的天堂爱欲| 国产护士精品抖阴版在线播放| 亚洲成AV人在线观看网址直播跳蛋| 精品精品国产国产国产国产国产国产 | 亚洲AV无码一区二区乱子伦,大香伊蕉 | 97精品一区二区视频在线观看| 日韩综合无码一区二区www|