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Rabbit Anti-EDG6/Gold Conjugated antibody (bs-2883R-Gold)
訂購熱線:400-901-9800
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-2883R-Gold
英文名稱1 Rabbit Anti-EDG6/Gold Conjugated antibody
中文名稱 膠體金標記的內皮細胞的分化蛋白6抗體
別    名 Endothelial differentiation lysophosphatidic acid G protein coupled receptor 6; Endothelial differentiation G protein coupled receptor 6; Endothelial differentiation gene 6; LPC1; Lysophospholipid receptor C1; MGC129298; Putative G protein coupled receptor; S1P receptor 4; S1P receptor Edg6; S1P4; S1PR4; SLP4; Sphingosine 1 phosphate receptor 4; Sphingosine 1 phosphate receptor Edg6; S1PR4_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 細胞生物  免疫學  轉錄調節因子  細胞膜受體  內皮細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Horse, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 42kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human EDG6/SLP4
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
This protein belongs to a G protein coupled heptahelical receptor subfamily named Endothelial Cell Differentiation Genes (EDG)that act as receptors for biologically active lysophospholipids. This group consists of two receptor subgroups specific for S1P and LPA respectively. EDG6 is the receptor for lysophospholipid sphingosine 1 phosphate (S1P). S1P elicits diverse physiological effect on most types of cells and tissues. EDG6 may be involved in cell migration processes that are specific for lymphocytes.

Function:
Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. May be involved in cell migration processes that are specific for lymphocytes.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Specifically expressed in fetal and adult lymphoid and hematopoietic tissue as well as in lung. Considerable level of expression in adult and fetal spleen as well as adult peripheral leukocytes and lung. Lower expression in adult thymus, lymph node, bone marrow, and appendix as well as in fetal liver, thymus, and lung.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:

Entrez Gene: 8698 Human

Entrez Gene: 13611 Mouse

Omim: 603751 Human

SwissProt: O95977 Human

SwissProt: Q9Z0L1 Mouse

Unigene: 662006 Human

Unigene: 33065 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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