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Rabbit Anti-PCDHA5/BF488 Conjugated antibody (bs-11119R-BF488)
訂購熱線:400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-11119R-BF488
英文名稱 Rabbit Anti-PCDHA5/BF488 Conjugated antibody
中文名稱 BF488標記的原鈣粘附蛋白α5抗體
別    名 Cadherin related neuronal receptor 6; CNR 6; CNR6; CNRN 6; CNRN6; CNRS 6; CNRS6; CRNR 6; CRNR6; Ortholog of mouse CNR6; PCDH alpha5; PCDHA 5; Protocadherin alpha 5; PCDA5_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 神經生物學  信號轉導  細胞粘附分子  細胞骨架  細胞外基質  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 99kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PCDHA5
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHA5 (Protocadherin alpha-5) is one of fifteen members of the protocadherin alpha protein family that is expressed in neurons. PCDHA5 is a 936 amino acid single-pass type I membrane protein containing 6 cadherin domains. Localized to the cell membrane, PCDHA5 functions as a calcium-dependent cell-adhesion protein that is present in synaptic junctions and is essential to the establishment and maintenance of certain cell-cell interactions. PCDHA5 is expressed as 3 isoforms produced by alternative splicing.

Function:
Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

Subcellular Location:
Cell membrane; Single pass type I membrane protein.

Similarity:
Contains 6 cadherin domains.

Database links:
UniProtKB/Swiss-Prot: Q9Y5H7.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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