| 產(chǎn)品編號(hào) | bs-11099R-APC |
| 英文名稱 | Rabbit Anti-NLGN4X/APC Conjugated antibody |
| 中文名稱 | APC標(biāo)記的神經(jīng)元X連鎖蛋白/兒童自閉癥相關(guān)蛋白抗體 |
| 別 名 | X-linked; HNLX; KIAA1260; Neuroligin X; Neuroligin-4; NLGN4; NLGN 4; NLGN4X; Neuroligin 4 X linked; Neuroligin 4; Neuroligin X; NLGN; NLGN-4; NLGN4X; NLGN4Y; NLGNX_HUMAN. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說(shuō) 明 書(shū) | 100ul |
| 研究領(lǐng)域 | 發(fā)育生物學(xué) 神經(jīng)生物學(xué) 細(xì)胞粘附分子 細(xì)胞膜蛋白 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Pig, Horse, Zebrafish, Chimpanzee, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 92kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NLGN4X |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. The encoded protein interacts with discs, large (Drosophila) homolog 4 (DLG4). Mutations in this gene have been associated with autism and Asperger syndrome. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]. Function: Putative neuronal cell surface protein involved in cell-cell-interactions. Subunit: Belongs to the type-B carboxylesterase/lipase family. Subcellular Location: Membrane. Tissue Specificity: Expressed at highest levels in heart. Expressed at lower levels in liver, skeletal muscle and pancreas and at very low levels in brain. DISEASE: Defects in NLGN4X may be the cause of susceptibility to autism X-linked type 2 (AUTSX2). AUTSX2 is a pervasive developmental disorder (PDD), prototypically characterized by impairments in reciprocal social interaction and communication, restricted and stereotyped patterns of interests and activities, and the presence of developmental abnormalities by 3 years of age. Defects in NLGN4X may be the cause of susceptibility to X-linked Asperger syndrome 2 (ASPGX2). ASPGX2 is considered to be a form of childhood autism. Similarity: Belongs to the type-B carboxylesterase/lipase family. Database links: Entrez Gene: 57502 Human Omim: 300427 Human SwissProt: Q8N0W4 Human Unigene: 21107 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
