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Rabbit Anti-CDC37/BF350 Conjugated antibody (bs-4290R-BF350)
訂購熱線:400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-4290R-BF350
英文名稱 Rabbit Anti-CDC37/BF350 Conjugated antibody
中文名稱 BF350標記的Hsp90輔助伴侶分子CDC37抗體
別    名 S cerevisiae hypothetical protein CDC37; CDC 37; CDC37; CDC37 cell division cycle 37 homolog; CDC37 cell division cycle 37 S cerevisiae homolog; Cdc37 homolog; CDC37 protein; CDC37_HUMAN; CDC37A; Cell division cycle 37 homolog; Hsp90 chaperone protein kinase targeting subunit; Hsp90 chaperone protein kinase targeting subunit p50Cdc37; Hsp90 chaperone protein kinase-targeting subunit; Hsp90 co chaperone Cdc37; Hsp90 co-chaperone Cdc37; p50; p50Cdc37.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  信號轉導  細胞周期蛋白  激酶和磷酸酶  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse,  (predicted: Rat, Dog, Pig, Cow, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 42kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CDC37
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity.

Function:
Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity.

Subunit:
Forms a complex with Hsp90/HSP90AB1 and CDK6. Interacts with AR, CDK4, CDK6, EIF2AK1 and RB1.

Subcellular Location:
Cytoplasm.

Post-translational modifications:
Constitutively sumoylated by UBE2I.

Similarity:
Belongs to the CDC37 family.

Database links:

Entrez Gene: 38232 Fruit fly (Drosophila melanogaster)

Entrez Gene: 11140 Human

Entrez Gene: 12539 Mouse

Entrez Gene: 114562 Rat

Omim: 605065 Human

SwissProt: Q24276 Fruit fly (Drosophila melanogaster)

SwissProt: Q16543 Human

SwissProt: Q61081 Mouse

SwissProt: Q63692 Rat

Unigene: 4857 Fruit fly (Drosophila melanogaster)

Unigene: 160958 Human

Unigene: 32331 Mouse

Unigene: 17982 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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