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Rabbit Anti-Histone H1.4 (Acetyl K53)/BF488 Conjugated antibody (bs-0931R-BF488)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-0931R-BF488
英文名稱1 Rabbit Anti-Histone H1.4 (Acetyl K53)/BF488 Conjugated antibody
中文名稱 BF488標記的乙酰化組蛋白H1b抗體
別    名 Histone H1.4(Ac-Lys53); Histone H1b (Ac-Lys53); Acetyl-Histone H1.4 (Lys53); Acetyl-Histone H1.4 (K53); HIST1H1E; H1F4; Histone H1.4; Histone H1b; H14_HUMAN; Histone H1s-4; H1 histone family member 4; H1E; Hist1h1e; Histone 1 H1e; Histone cluster 1 H1e; Histone H1; MGC116819.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
產品類型 乙酰化抗體 
研究領域 腫瘤  發育生物學  信號轉導  細胞凋亡  轉錄調節因子  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse,  (predicted: Rat, Dog, Pig, Cow, Horse, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 24kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated Synthesised acetylpeptide derived from human Histone H1b around the acetylation site of Lys53
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Histone H1b are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

Function:
Histones H1 are necessary for the condensation of nucleosome chains into higher order structures.

Subcellular Location:
Nucleus. Chromosome.

Post-translational modifications:
Acetylated at Lys-26. Deacetylated at Lys-26 by SIRT1.

Similarity:
Belongs to the histone H1/H5 family.
Contains 1 H15 (linker histone H1/H5 globular) domain.

Database links:

Entrez Gene: 3008 Human

Omim: 142220 Human

SwissProt: P10412 Human

Unigene: 248133 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

轉錄調節因子(Transcriptin Regulators)
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