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Rabbit Anti-intestinal FABP/AP Conjugated antibody (bs-0898R-AP)
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說(shuō) 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-0898R-AP
英文名稱1 Rabbit Anti-intestinal FABP/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標(biāo)記的小腸型脂肪酸結(jié)合蛋白抗體
別    名 FABP 2; FABP2; FABPI; Fatty acid binding protein 2 intestinal; Fatty acid binding protein intestinal; Fatty acid-binding protein; I-FABP; I FABP; IFABP; Intestinal fatty acid binding protein 2; MGC133132; FABPI_HUMAN; Fatty acid binding protein intestinal; Fatty acid-binding protein 2; Fatty acid-binding protein; Intestinal fatty acid binding protein 2; Intestinal-type fatty acid-binding protein; OTTHUMP00000163925.   
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書 100ul  
研究領(lǐng)域 免疫學(xué)  生長(zhǎng)因子和激素  激酶和磷酸酶  糖尿病  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, )
產(chǎn)品應(yīng)用 IHC-P=1:50-200 IHC-F=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 28kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human IFABP
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor (By similarity). [Subcellular Location] Cytoplasm (By similarity). [Similarity] Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

Function:
FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Expressed in the small intestine and at much lower levels in the large intestine. Highest expression levels in the jejunum.

Similarity:
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

Database links:

Entrez Gene: 2169 Human

Entrez Gene: 14079 Mouse

Entrez Gene: 25598 Rat

Omim: 134640 Human

SwissProt: P12104 Human

SwissProt: P55050 Mouse

SwissProt: Q53YP5 Mouse

SwissProt: P02693 Rat

Unigene: 282265 Human

Unigene: 28398 Mouse

Unigene: 91358 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

小腸脂肪酸結(jié)合蛋白(IFABP)主要是在小腸分泌的一種蛋白質(zhì),參與了脂肪酸的吸收和代謝。IFABP有可能通過(guò)干擾脂肪酸代謝而影響胰島素敏感性。 IFABP主要用于2型糖尿病相關(guān)性的研究。
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