產(chǎn)品編號 | BIO0037SM |
英文名稱 | Anti-human ERBB2 / HER2 / CD340 (Trastuzumab Biosimilar) |
中文名稱 | |
抗體來源 | |
克隆類型 | Monoclonal |
交叉反應(yīng) | Human,Mouse |
產(chǎn)品應(yīng)用 |
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 145.36 kDa |
檢測分子量 | |
性 狀 | Lyophilized |
亞 型 | Human IgG1 |
純化方法 | Protein A |
保存條件 | For long term storage, the produce should be stored at -20°C or lower. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 | |
產(chǎn)品圖片 |
Trastuzumab inhibited the tumor growth of BT474 on NCG mice. The result showed significant anti-tumor effects, with an tumor inhibition rate (TGI) of 88.5% at 10 mpk at D35.
BT474 cells were stained with Anti-ERBB2 / HER2 / CD340 Reference Antibody (trastuzumab) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC50=0.3024 ug/mL.
Immobilized human HER2, His at 2 ug/mL can bind Anti-ERBB2 / HER2 / CD340 Reference Antibody (trastuzumab), EC50=0.005735 ug/mL.
The purity of Anti-ERBB2 / HER2 / CD340 Reference Antibody (trastuzumab) is more than 95%, determined by SEC-HPLC.
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