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SLC19A1 Rabbit pAb (bs-20879R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產品編號 bs-20879R
英文名稱 SLC19A1 Rabbit pAb
中文名稱 溶質載體家族蛋白19成員A1抗體
別    名 CHMD; FLOT 1; FLOT1; Folate transporter 1; FOLT; IFC 1; IFC-1; IFC1; Intestinal folate carrier 1; Intestinal folate carrier; OTTHUMP00000115459; OTTHUMP00000115460; Placental folate transporter; Reduced folate carrier; Reduced folate carrier protein; REFC; RFC 1; RFC; RFC1; S19A1_MOUSE; SLC19A1; Solute carrier family 19 member 1.  
研究領域 腫瘤  細胞生物  信號轉導  轉運蛋白  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Mouse,Rat)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 64 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse SLC19A1: 101-200/512 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 SLC19A1 (Solute Carrier Family 19 (Folate Transporter), Member 1) is a Protein Coding gene. Diseases associated with SLC19A1 include placental choriocarcinoma and thiamine-responsive megaloblastic anemia syndrome. Among its related pathways are Cell Cycle, Mitotic and Metabolism. GO annotations related to this gene include oxidoreductase activity and folic acid transporter activity. An important paralog of this gene is SLC19A2.

Function:
Transporter for the intake of folate. Uptake of folate in human placental choriocarcinoma cells occurs by a novel mechanism called potocytosis which functionally couples three components, namely the folate receptor, the folate transporter, and a V-type H(+)-pump.

Subcellular Location:
Membrane.

Tissue Specificity:
Placenta, liver, and to a much smaller extent, in lung.

Post-translational modifications:
Heavily glycosylated.

Similarity:
Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.

SWISS:
P41438

Gene ID:
20509

Database links:

Entrez Gene: 6573 Human

Entrez Gene: 20509 Mouse

Entrez Gene: 29723 Rat

Omim: 600424 Human

SwissProt: P41440 Human

SwissProt: P41438 Mouse

SwissProt: Q62866 Rat

Unigene: 84190 Human

Unigene: 9042 Rat




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