| 產(chǎn)品編號 | bs-20683R |
| 英文名稱 | IL-22 Rabbit pAb |
| 中文名稱 | 白介素-22抗體 |
| 別 名 | Interleukin-22; Il22; Iltif; ILTIFa; MGC129416; MGC129417; IL-10-related T-cell-derived-inducible factor; IL-TIF; ILTIF; IL-TIF alpha; Interleukin-22a; IL-22a; IL 21; IL D110; IL TIF; IL21; IL22; ILD110; interleukin 21; MGC79382; MGC79384; TIFa; TIFIL 23; TIFIL-23; TIFIL23; zcyto18; Cytokine Zcyto18. |
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Specific References (1) | bs-20683R has been referenced in 1 publications.
[IF=5.307] Xu Zhou. et al. Magnesium isoglycyrrhizinate ameliorates lipopolysaccharide-induced liver injury by upregulating autophagy and inhibiting inflammation via IL-22 expression. BIOORG CHEM. 2022 Nov;128:106034 IHC, WB ; Mouse.
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| 研究領(lǐng)域 | 免疫學(xué) 生長因子和激素 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human (predicted: Mouse,Rat,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 17 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human IL-22: 81-150/179 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene was identified by its overexpression specifically in herpesvirus samimiri-transformed T cells. The encoded protein is a member of the IL10 family of cytokines. It is a secreted protein and may function as a homodimer. This protein is thought to contribute to the transformed phenotype of T cells after infection by herpesvirus samimiri. [provided by RefSeq]. Function: Cytokine that contributes to the inflammatory response in vivo. Subcellular Location: Secreted. Similarity: Belongs to the IL-10 family. SWISS: Q9GZX6 Gene ID: 50616 Database links: Entrez Gene: 50616 Human Entrez Gene: 50929 Mouse Omim: 605330 Human SwissProt: Q9GZX6 Human SwissProt: Q9JJY9 Mouse Unigene: 287369 Human Unigene: 103585 Mouse Unigene: 195879 Rat IL-22是白介素-10家族的成員,主要是由激活的T 淋巴細(xì)胞產(chǎn)生的一類重要的細(xì)胞因子,除了在Th17細(xì)胞中高表達(dá)之外，在NK和NKT等細(xì)胞中也有表達(dá),在組織損傷修復(fù)以及牛皮癬、肝炎、肺炎、腸炎等慢性炎癥中發(fā)揮重要作用.IL-22是繼IL-6和IL-10之后又一個參與炎癥反應(yīng)和代謝調(diào)控的細(xì)胞因子，IL-22有可能成為干預(yù)脂肪肝發(fā)生發(fā)展的新方法。 |
