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Rabbit Anti-SLC25A24  antibody (bs-21226R)  
~~~促銷代碼KT202411~~~
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產品編號 bs-21226R
英文名稱 Rabbit Anti-SLC25A24  antibody
中文名稱 溶質載體家族25成員24抗體
別    名 APC 1; APC1; Calcium binding mitochondrial carrier protein SCaMC 1; Calcium binding transporter; DKFZp586G0123; MCSC 1; MCSC1; Mitochondrial ATP Mg/Pi carrier protein 1; Mitochondrial ATP Mg/Pi transporter; Mitochondrial Ca(2+) dependent solute carrier protein 1; OTTHU.MP00000012674; SCAMC 1; SCAMC1; Short calcium binding mitochondrial carrier 1; Slc25a24; Small calcium binding mitochondrial carrier protein 1; Solute carrier family 25 (mitochondrial carrier phosphate carrier) member 24; Solute carrier family 25 member 24.  
Specific References  (1)     |     bs-21226R has been referenced in 1 publications.
[IF=8.469] Chen, Yan-Jie. et al. An integrated bioinformatic investigation of mitochondrial solute carrier family 25 (SLC25) in colon cancer followed by preliminary validation of member 5 (SLC25A5) in tumorigenesis. Cell Death Dis. 2022 Mar;13(3):1-16  IHC ;  Human.  
研究領域 細胞生物  信號轉導  轉運蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 53kDa
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SLC25A24: 121-220/477 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 SLC25A24 (Solute carrier family 25 member 24) is a calcium-dependent mitochondrial solute carrier. It may act as a ATP-Mg/Pi exchanger that mediates the transport of Mg-ATP in exchange for phosphate, catalyzing the net uptake or efflux of adenine nucleotides into or from the mitochondria.

Function:
Calcium-dependent mitochondrial solute carrier. Mediates the reversible, electroneutral exchange of Mg-ATP or Mg-ADP against phosphate ions, catalyzing the net uptake or efflux of adenine nucleotides across the mitochondrial inner membrane. Nucleotide transport is inactive when cytosolic calcium levels are low, and is activated by an increase in cytosolic calcium levels. May play a role in protecting cells against oxidative stress-induced cell death, probably by promoting the formation of calcium-phosphate precipitates in the mitochondrial matrix, and thereby buffering calcium levels in the mitochondrial matrix.

Tissue Specificity:
Present in various cell lines (at protein level). Expressed in all tissues tested. Highly expressed in testis, expressed at intermediate level in small intestine and pancreas, and weakly expressed in kidney, spleen, liver, skeletal muscle and heart.

Similarity:
Belongs to the mitochondrial carrier (TC 2.A.29) family.

SWISS:
Q6NUK1

Gene ID:
29957

Database links:

Entrez Gene: 29957 Human

Omim: 608744 Human

SwissProt: Q6NUK1 Human



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