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RBMS1/Cervical cancer oncogene 4 Rabbit pAb (bs-19776R)  
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產品編號 bs-19776R
英文名稱 RBMS1/Cervical cancer oncogene 4 Rabbit pAb
中文名稱 宮頸癌癌基因4抗體
別    名 c myc gene single strand binding protein 2; C2orf12; Cervical cancer oncogene 4; HCC 4; MSSP 2; MSSP 3; MSSP; MSSP-1; MSSP-2; MSSP-3; MSSP1; RBMS1; RBMS1_HUMAN; RNA binding motif, single stranded interacting protein 1; RNA-binding motif; SCR2; Single stranded DNA binding protein MSSP 1; Single-stranded DNA-binding protein MSSP-1; single-stranded-interacting protein 1; suppressor of cdc 2(cdc13) with RNA binding motif 2; Suppressor of CDC2 with RNA binding motif 2; Suppressor of CDC2 with RNA-binding motif 2; YC1.  
研究領域 腫瘤  細胞凋亡  細胞周期蛋白  轉錄調節因子  結合蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse (predicted: Human,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 45 kDa
檢測分子量
細胞定位 細胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RBMS1/Cervical cancer oncogene 4: 181-280/406 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. Several transcript variants, resulting from alternative splicing and encoding different isoforms, have been described. A pseudogene for this locus is found on chromosome 12. [provided by RefSeq, Feb 2009]

Function:
Single-stranded DNA binding protein that interacts with the region upstream of the MYC gene. Binds specifically to the DNA sequence motif 5'-[AT]CT[AT][AT]T-3'. Probably has a role in DNA replication.

Subcellular Location:
Nucleus.

Tissue Specificity:
Highest amounts are found in placenta, lung and heart.

Similarity:
Contains 2 RRM (RNA recognition motif) domains.

SWISS:
P29558

Gene ID:
5937

Database links:

Entrez Gene: 395880 Chicken

Entrez Gene: 526135 Cow

Entrez Gene: 5937 Human

Entrez Gene: 56878 Mouse

Entrez Gene: 362138 Rat

GenBank: NP_058520.1 Human

Omim: 602310 Human

SwissProt: Q3ZBP3 Cow

SwissProt: P29558 Human

SwissProt: Q91W59 Mouse

SwissProt: Q5PQP1 Rat

Unigene: 470412 Human

Unigene: 708357 Human

Unigene: 259667 Mouse

Unigene: 482338 Mouse

Unigene: 98522 Rat



產品圖片
Sample: Heart (Mouse) Lysate at 40 ug Heart (Mouse) Lysate at 40 ug Primary: Anti-RBMS1 (bs-19776R) at 1/500 dilution Anti-RBMS1 (bs-19776R) at 1/20000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 45 kD Observed band size: 50 kD
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