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Rabbit Anti-LY6H  antibody (bs-18455R)  
~~~促銷代碼KT202411~~~
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產品編號 bs-18455R
英文名稱 Rabbit Anti-LY6H  antibody
中文名稱 淋巴細胞抗原6H抗體
別    名 Ly-6H; LY 6H; Lymphocyte antigen 6 complex locus H; Lymphocyte antigen 6H; NMLY 6; NMLY6.  
研究領域 細胞生物  免疫學  淋巴細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Pig,Sheep,Cow,Horse)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 12kDa
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LY6H: 21-100/140 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The Ly-6 (Lymphocyte antigen 6) alloantigens represent a family of phosphatidylinositol-anchored proteins that play a role in the process of T lymphocyte activation. Ly-6 family members share amino acid homology throughout a distinctive cysteine rich protein domain that incorporates O-linked carbohydrates. During hematopoiesis, murine Ly-6 molecules have unique patterns of tissue expression, from multipotential stem cells to lineage committed precursor cells, and on specific leukocyte subpopulations in the peripheral lymphoid tissues. Ly-6H (Lymphocyte antigen 6H), also known as NMLY6, is a 140 amino acid lipid-anchored membrane protein that belongs to the Ly-6 family. Highly expressed in brain with lower expression in pancreas, testis, colon and small intestine, Ly-6H participates in the activation of T lymphocytes. Overexpression of Ly-6H is detected in certain acute human leukemic cell lines (such as MOLT-3), suggesting a possible role for Ly-6H in carcinogenesis.

Subcellular Location:
Cell membrane. Lipid-anchor, GPI-anchor.

Tissue Specificity:
Highly expressed in brain (cerebral cortex, amygdala, hippocampus and subthalamic nucleus) and in acute human leukemic cell line MOLT-3. Also found in lower levels in testis, pancreas, small intestine and colon.

SWISS:
O94772

Gene ID:
4062

Database links:

Entrez Gene: 4062 Human

Omim: 603625 Human

SwissProt: O94772 Human

Unigene: 159590 Human



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