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Rabbit Anti-KCNS1  antibody (bs-16916R)  
~~~促銷代碼KT202411~~~
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產品編號 bs-16916R
英文名稱 Rabbit Anti-KCNS1  antibody
中文名稱 電壓門控鉀通道亞基KV9.1抗體
別    名 Delayed rectifier K(+) channel alpha subunit 1; Delayed-rectifier K(+) channel alpha subunit 1; K+ voltage gated channel, subfamily S, 1; KCNS1; KCNS1_HUMAN; KV9.1; OTTHUMP00000031783; potassium voltage gated channel delayed rectifier protein; potassium voltage gated channel delayed rectifier protein S1; potassium voltage gated channel, delayed rectifier, subfamily S, member 1; Potassium voltage-gated channel subfamily S member 1; voltage gated potassium channel protein Kv9.1; Voltage gated potassium channel subunit Kv9.1; Voltage-gated potassium channel subunit Kv9.1.  
研究領域 腫瘤  神經生物學  信號轉導  通道蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Rat (predicted: Human,Mouse,Cow,Dog,Horse)
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 58kDa
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KCNS1: 161-260/526 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Voltage-gated potassium channels form the largest and most diversified class of ion channels and are present in both excitable and nonexcitable cells. Their main functions are associated with the regulation of the resting membrane potential and the control of the shape and frequency of action potentials. The alpha subunits are of 2 types: those that are functional by themselves and those that are electrically silent but capable of modulating the activity of specific functional alpha subunits. The protein encoded by this gene is not functional by itself but can form heteromultimers with member 1 and with member 2 (and possibly other members) of the Shab-related subfamily of potassium voltage-gated channel proteins. This gene belongs to the S subfamily of the potassium channel family. [provided by RefSeq, Jul 2008]

Function:
Potassium channel subunit. Modulates channel activity and reduces the ion flow.

Subcellular Location:
Cell membrane. May not reach the plasma membrane but remain in an intracellular compartment in the absence of KCNB1.

Tissue Specificity:
Detected in all tissues tested with the exception of skeletal muscle. Highly expressed in adult and fetal brain, fetal kidney and lung, and adult prostate and testis.

Similarity:
Belongs to the potassium channel family. S (TC 1.A.1.2) subfamily. Kv9.1/KCNS1 sub-subfamily.

SWISS:
Q96KK3

Gene ID:
3787

Database links:

Entrez Gene: 3787 Human

Omim: 602905 Human

SwissProt: Q96KK3 Human

Unigene: 117780 Human



產品圖片
Sample: Heart(Rat) Cell Lysate at 40 ug Primary: Anti-KCNS1 (bs-16916R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 58 kD Observed band size: 58 kD
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