| 產(chǎn)品編號(hào) | bs-16886R |
| 英文名稱 | Rabbit Anti-KCNH5 antibody |
| 中文名稱 | KCNH5蛋白抗體 |
| 別 名 | EAG2; Ether a go go potassium channel 2; H EAG2; HGNC:6254; Kv10.2; potassium voltage gated channel subfamily H (eag-related) member 5; Voltage gated potassium channel subunit Kv10.2. |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 通道蛋白 新陳代謝 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human (predicted: Mouse,Rat,Pig,Sheep,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 112kDa |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human KCNH5: 351-450/988 <Extracellular> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. The KCNH5 gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. KCNH5 is not expressed in differentiating myoblasts. Subunit: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits. Heteromultimer with KCNH1/EAG (Probable). Subcellular Location: Cell Membrane: multi-pass membrane protein. Tissue Specificity: Detected in brain, skeletal muscle, heart,placenta, lung and liver, and at low levels in kidney. Similarity: Belongs to the potassium channel family. Contains 1 cyclic nucleotide-binding domain. Contains 1 PAS (PER-ARNT-SIM) domain. Contains 1 cyclic nucleotide-binding domain. ] Contains 1 PAS (PER-ARNT-SIM) domain. SWISS: Q8NCM2 Gene ID: 27133 Database links: Entrez Gene: 27133 Human Entrez Gene: 238271 Mouse Omim: 605716 Human SwissProt: Q8NCM2 Human SwissProt: Q6NZH0 Mouse SwissProt: Q920E3 Mouse Unigene: 27043 Human Unigene: 48753 Rat |
| 產(chǎn)品圖片 |
Sample:
Hcclm3(Human) Cell Lysate at 30 ug
Primary: Anti-KCNH5 (bs-16886R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 112 kD
Observed band size: 117 kD
Sample:
HepG2(Human) Cell Lysate at 30 ug
Primary: Anti-KCNH5 (bs-16886R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 112 kD
Observed band size: 117 kD
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