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FBXO16 Rabbit pAb (bs-16046R)  
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產品編號 bs-16046R
英文名稱 FBXO16 Rabbit pAb
中文名稱 FBXO16蛋白抗體
別    名 FBXO16; F box only protein 16; F box protein 16; FBX16; FBXO 16; FBX16_HUMAN; MGC125923; MGC125924; MGC125925.  
研究領域 細胞生物  免疫學  轉運蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 35 kDa
檢測分子量
細胞定位 細胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FBXO16: 1-100/292 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbx class. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]

Function:
FBXO16 is a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. FBXO16 probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. It is expressed in heart, spleen and colon.

Subunit:
Part of a SCF (SKP1-cullin-F-box) protein ligase complex (By similarity).

Tissue Specificity:
Expressed in heart, spleen and colon.

Similarity:
Contains 1 F-box domain.

SWISS:
Q8IX29

Gene ID:
157574

Database links:

Entrez Gene: 157574 Human

Entrez Gene: 50759 Mouse

Entrez Gene: 305970 Rat

Omim: 608519 Human

SwissProt: Q8IX29 Human

SwissProt: Q9QZM9 Mouse



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