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Rabbit Anti-C7orf44  antibody (bs-15269R)  
~~~促銷代碼KT202411~~~
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產品編號 bs-15269R
英文名稱 Rabbit Anti-C7orf44  antibody
中文名稱 7號染色體開放閱讀框44抗體
別    名 Chromosome 7 open reading frame 44; FLJ10803; Hypothetical protein LOC55744; Uncharacterized protein C7orf44;COA1_HUMAN.   
研究領域 細胞生物  免疫學  線粒體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human)
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 17kDa
細胞定位 細胞漿 線粒體
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human C7orf44: 51-146/146 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia. The C7orf44 gene product has been provisionally designated C7orf44 pending further characterization.

Function:
Component of some MITRAC complex, a cytochrome c oxidase (COX) assembly intermediate complex that regulates COX assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for assembly of mitochondrial respiratory chain complex I and complex IV.

Subunit:
Interacts with COX17 and COA6. Component of some MITRAC complex.

Subcellular Location:
Mitochondrion inner membrane; Single-pass membrane protein.

Similarity:
Belongs to the COA1 family.

SWISS:
Q9GZY4

Gene ID:
55744

Database links:

Entrez Gene: 55744 Human

SwissProt: Q9GZY4 Human



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