| 產品編號 | bs-12467R |
| 英文名稱 | Rabbit Anti-AMBN antibody |
| 中文名稱 | 釉基質蛋白抗體 |
| 別 名 | AMBN; AMBN_HUMAN; Ameloblastin (enamel matrix protein); Ameloblastin. |
 |
Specific References (1) | bs-12467R has been referenced in 1 publications.
[IF=3.606] Xie, Yongting. et al. Amelogenesis imperfecta in a Chinese family resulting from a FAM83H variation and the effect of FAM83H on the secretion of enamel matrix proteins. CLIN ORAL INVEST. 2022 Nov;:1-11 WB ; Rat.
|
| 研究領域 | 細胞生物 信號轉導 細胞骨架 細胞外基質 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應 | (predicted: Human,Mouse,Rat,Rabbit,Sheep,Cow,Dog,Horse) |
| 產品應用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 45kDa |
| 細胞定位 | 細胞外基質 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human AMBN: 21-120/447 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產品介紹 |
Dental enamel is a highly mineralized tissue with most of its volume occupied by large, highly organized, hydroxyapatite crystals. This structure is thought to be controlled through the interaction of many organic matrix molecules including amelogenin, ameloblastin, enamelin, tuftelin and several other enzymes. All of these secreted proteins are involved in the mineralization and enamel matrix formation in developing tooth enamel. Ameloblastin (AMBN), which localizes to the extracellular matrix, is an ameloblast-specific protein. It is detected in the sheath space between rod-interrod enamel and at the Tomes processes of secretory ameloblasts. Defects in the gene encoding for ameloblastin, AMBN, can be seen in patients with ameloblastomas. Function: Involved in the mineralization and structural organization of enamel. Subcellular Location: Secreted > extracellular space > extracellular matrix. Tissue Specificity: Ameloblast-specific. Located at the Tomes processes of secretory ameloblasts and in the sheath space between rod-interrod enamel. Similarity: Belongs to the ameloblastin family. SWISS: Q9NP70 Gene ID: 258 Database links: Entrez Gene: 258 Human Omim: 601259 Human SwissProt: Q9NP70 Human Unigene: 272396 Human |
| 1、抗體溶解方法 | |
| 2、抗體修復方式 | |
| 3、常用試劑的配制 | |
| 4、免疫組化操作步驟 | |
| 5、免疫組化問題解答 | |
| 6、Western Blotting 操作步驟 | |
| 7、Western Blotting 問題解答 | |
| 8、關于肽鏈的設計 | |
| 9、多肽的溶解與保存 | |
| 10、酶標抗體效價測定程序 | |
