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Adrenodoxin Rabbit pAb (bs-11426R)  
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產品編號 bs-11426R
英文名稱 Adrenodoxin Rabbit pAb
中文名稱 腎上腺皮質線粒體鐵氧還蛋白抗體
別    名 Adrenal ferredoxin; Adrenodoxin; Adrenodoxin, mitochondrial; ADX; ADX_HUMAN; FDX; fdx1; Ferredoxin 1; Ferredoxin-1; Hepatoredoxin; LOH11CR1D; Mitochondrial adrenodoxin; mitochondrial.  
Specific References  (1)     |     bs-11426R has been referenced in 1 publications.
[IF=8.786] Jiateng Hu. et al. Identification of core cuprotosis-correlated biomarkers in abdominal aortic aneurysm immune microenvironment based on bioinformatics. FRONT IMMUNOL. 2023; 14: 1138126  IF ;  Mouse.  
研究領域 腫瘤  細胞生物  神經生物學  信號轉導  生長因子和激素  線粒體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Rat (predicted: Human,Mouse,Sheep)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 13.5 kDa
檢測分子量
細胞定位 細胞漿 線粒體
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Adrenodoxin/FDX: 51-150/184 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes a small iron-sulfur protein that transfers electrons from NADPH through ferredoxin reductase to mitochondrial cytochrome P450, involved in steroid, vitamin D, and bile acid metabolism. Pseudogenes of this functional gene are found on chromosomes 20 and 21. [provided by RefSeq, Aug 2011]

Function:
Participates in the synthesis of thyroid hormones. Transfers electrons from adrenodoxin reductase to the cholesterol side chain cleavage cytochrome P450.

Subcellular Location:
Mitochondrion matrix.

Tissue Specificity:
Highest levels in the adrenal gland (at protein level). Also detected in kidney and testis (at protein level).

Similarity:
Belongs to the adrenodoxin/putidaredoxin family.
Contains 1 2Fe-2S ferredoxin-type domain.

SWISS:
P10109

Gene ID:
2230

Database links:

Entrez Gene: 2230 Human

Entrez Gene: 14148 Mouse

Entrez Gene: 29189 Rat

Omim: 103260 Human

SwissProt: P10109 Human

SwissProt: P46656 Mouse

SwissProt: P24483 Rat

Unigene: 744 Human

Unigene: 1061 Mouse

Unigene: 440190 Mouse

Unigene: 6946 Rat



產品圖片
Paraformaldehyde-fixed, paraffin embedded (rat adrenal gland tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Adrenodoxin) Polyclonal Antibody, Unconjugated (bs-11426R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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