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MAP-9 Rabbit pAb (bs-9313R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產品編號 bs-9313R
英文名稱 MAP-9 Rabbit pAb
中文名稱 微管相關蛋白9抗體
別    名 ASAP; Aster associated protein; MAP9; MAP 9; microtubule associated protein 9; MAP9_HUMAN.  
研究領域 細胞生物  信號轉導  細胞周期蛋白  細胞分化  細胞骨架  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse)
產品應用 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 74 kDa
檢測分子量
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MAP-9: 1-100/647 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Microtubules, the primary component of the cytoskeletal network, interact with proteins called microtubule-associated proteins (MAPs).MAP9 is a microtubule-associated protein required for spindle function, mitotic progression, and cytokinesis.The microtubule-associated proteins can be divided into two groups, structural and dynamic. The MAP proteins function to stimulate tubulin assembly, enhance microtubule stability, influence the spatial distribution of microtubules within cells and utilize microtubule polarity to translocate cellular components. MAP-9 (microtubule-associated protein 9), also known as ASAP, is a 647 amino acid cytoplasmic protein that is constitutively expressed during the cell cycle. MAP-9 localizes to microtubules in interphase, associates with the mitotic spindle during mitosis and localizes to the central body during cytokinesis. Involved in organization of the bipolar mitotic spindle, MAP-9 is required for bipolar spindle assembly, mitosis progression and cytokinesis. MAP-9 may be involved in stabilizing interphase microtubules. Two isoforms of MAP-9 are produced due to alternative splicing events.

Function:
Involved in organization of the bipolar mitotic spindle. Required for bipolar spindle assembly, mitosis progression and cytokinesis. May act by stabilizing interphase microtubules.

Subunit:
Binds to purified microtubules via its C-terminus.

Subcellular Location:
Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Note=Localizes to microtubules in interphase, associates with the mitotic spindle during mitosis, localizes to the central body during cytokinesis.

SWISS:
Q49MG5

Gene ID:
79884

Database links:

Entrez Gene: 79884 Human

Omim: 610070 Human

SwissProt: Q49MG5 Human

Unigene: 61271 Human



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