| 產品編號 | bs-8271R |
| 英文名稱 | Rabbit Anti-GIMAP5 antibody |
| 中文名稱 | GTP酶IMAP家族成員5抗體 |
| 別 名 | HIMAP3; IAN4; IAN4L1; IAN5; IMAP3; FLJ11296; GIMAP 5; GTPase IMAP family member 5; GTPase, IMAP family member 5; immunity-associated nucleotide 5; hIAN5; IAN 5; Immune associated nucleotide 4 like 1; Immunity associated nucleotide 4 like 1 protein; Immunity associated protein 3; GIMA5_HUMAN. |
| 研究領域 | 細胞生物 免疫學 信號轉導 t-淋巴細胞 G蛋白信號 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應 | Human |
| 產品應用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 35kDa |
| 細胞定位 | 細胞漿 細胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GIMAP5: 101-200/307 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產品介紹 |
GIMAP5, also known as IAN5, IAN4L1 (immunity-associated nucleotide 4-like 1 protein), IAN4, IMAP3, HIMAP3 or IROD, is a 307 amino acid single-pass type IV membrane protein of the mitochondrial outer membrane. A member of the GTP-binding superfamily and the immuno-associated nucleotide (IAN) subfamily, GIMAP5 plays a role in T-cell survival and mitochondrial integrity. GIMAP5 is highly expressed in CD4 and CD8-positive T-cells and monocytes, as well as B-lymphocyte-derived neoplasms. GIMAP5 exists as two alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 7q36.1. Defects in the GIMAP5 gene are associated with systemic lupus erythematosus. Function: Required for mitochondrial integrity and T-cell survival. May contribute to T-cell quiescence (By similarity). Subcellular Location: Mitochondrion outer membrane; Single-pass type IV membrane protein (By similarity). Lysosome. Tissue Specificity: Widely expressed with high levels in lymph node and spleen. High expression found in CD4 and CD8-positive T-cells and monocytes with very low levels in B-lymphocytes. Highly expressed in B-lymphocyte-derived neoplasms. Similarity: Belongs to the IAN GTP-binding protein family. SWISS: Q96F15 Gene ID: 55340 Database links: Entrez Gene: 55340 Human Omim: 608086 Human SwissProt: Q96F15 Human Unigene: 647079 Human Unigene: 698139 Human |
| 產品圖片 |
Sample:
U937 (Human) Cell Lysate at 30 ug
Primary: Anti-GIMAP5 (bs-8271R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 35 kD
Observed band size: 35 kD
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| 1、抗體溶解方法 | |
| 2、抗體修復方式 | |
| 3、常用試劑的配制 | |
| 4、免疫組化操作步驟 | |
| 5、免疫組化問題解答 | |
| 6、Western Blotting 操作步驟 | |
| 7、Western Blotting 問題解答 | |
| 8、關于肽鏈的設計 | |
| 9、多肽的溶解與保存 | |
| 10、酶標抗體效價測定程序 | |
