| 產品編號 | bs-8069R |
| 英文名稱 | SRRM4 Rabbit pAb |
| 中文名稱 | 絲氨酸/精氨酸相關核基質蛋白4抗體 |
| 別 名 | Neural-specific serine/arginine repetitive splicing factor of 100 kDa; Neural-specific SR-related protein of 100 kDa; nSR100; Serine/arginine repetitive matrix protein 4; Srrm4; SRRM4_HUMAN. |
| 研究領域 | 細胞生物 發育生物學 神經生物學 信號轉導 細胞周期蛋白 細胞分化 表觀遺傳學 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應 | (predicted: Human,Mouse,Rat,Sheep,Cow,Chicken,Dog) |
| 產品應用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 69 kDa |
| 檢測分子量 | |
| 細胞定位 | 細胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SRRM4: 451-611/611 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產品介紹 |
Splicing factor specifically required for neural cell differentiation. Acts in conjuction with nPTB/PTBP2 by binding directly to its regulated target transcripts and promotes neural-specific exon inclusion in many genes that function in neural cell differentiation. Required to promote the inclusion of neural-specific exon 10 in nPTB/PTBP2, leading to increased expression of neural-specific nPTB/PTBP2. Also promotes the inclusion of exon 16 in DAAM1 in neuron extracts. Function: Splicing factor specifically required for neural celldifferentiation. Acts in conjuction with nPTB/PTBP2 by bindingdirectly to its regulated target transcripts and promotesneural-specific exon inclusion in many genes that function inneural cell differentiation. Required to promote the inclusion ofneural-specific exon 10 in nPTB/PTBP2, leading to increasedexpression of neural-specific nPTB/PTBP2. Also promotes theinclusion of exon 16 in DAAM1 in neuron extracts (By similarity). Subcellular Location: Nucleus (By similarity). Tissue Specificity: Specifically expressed in neuronal cells (atprotein level). Expressed in the cerebellum. Post-translational modifications: Phosphorylated (By similarity). Similarity: Belongs to the nSR100 family. SWISS: A7MD48 Gene ID: 84530 Database links: Entrez Gene: 84530 Human Entrez Gene: 68955 Mouse SwissProt: A7MD48 Human SwissProt: Q8BKA3 Mouse Unigene: 726207 Human Unigene: 146779 Mouse |
| 1、抗體溶解方法 | |
| 2、抗體修復方式 | |
| 3、常用試劑的配制 | |
| 4、免疫組化操作步驟 | |
| 5、免疫組化問題解答 | |
| 6、Western Blotting 操作步驟 | |
| 7、Western Blotting 問題解答 | |
| 8、關于肽鏈的設計 | |
| 9、多肽的溶解與保存 | |
| 10、酶標抗體效價測定程序 | |
